Table 2.

Expression of CXCR3 or CXCR4 on Vδ1 or Vδ2 T cells in peripheral blood of HIV-1—infected patients and healthy donors




Vδ2+

Vδ2+ CXCR3+

Vδ2+ CXCR4+

Vδ1+

Vδ1+ CXCR3+

Vδ1+ CXCR4+
Patients        
1   1.0   0.9   0.9   1.0   0.8   1.0  
2   1.6   1.5   1.6   1.2   1.0   1.2  
3   0.7   0.6   0.7   1.4   1.3   1.2  
4   1.9   1.8   1.7   2.2   1.8   2.0  
5   0.7   0.7   0.7   4.2   3.2   3.6  
6   2.7   2.8   2.3   4.1   2.0   3.9  
7   0.3   0.2   0.3   1.0   0.9   1.1  
8   3.8   2.8   3.1   2.2   1.6   1.8  
9   0.4   0.3   0.4   2.3   2.0   1.9  
10   2.4   2.3   2.6   2.9   1.9   2.9  
11   0.3   0.2   0.3   8.8   4.3   8.6  
12   1.3   1.3   1.2   2.7   1.7   1.4  
13   1.1   1.0   1.3   2.3   1.6   2.0  
14   3.0   1.9   1.6   1.2   1.0   1.2  
15   1.0   0.9   0.7   2.2   1.3   2.2  
16   3.2   2.4   2.0   4.1   2.3   3.9  
17   3.5   2.2   1.0   4.2   2.0   1.7  
18   4.0   3.3   1.1   9.2   2.9   4.8  
19   2.0   1.9   1.0   0.9   0.6   0.4  
20   1.8   1.4   1.3   4.4   3.3   3.3  
21   3.4   2.9   2.6   9.3   7.3   6.4  
22   1.4   1.4   1.6   2.7   1.7   2.7  
23   0.4   0.2   0.2   2.0   0.8   0.6  
24   4.8   3.8   4.8   3.0   2.9   2.0  
25   3.3   2.5   3.2   1.8   1.5   1.7  
26   2.2   0.8   0.4   3.6   1.2   0.7  
27   2.0   2.0   2.2   2.7   1.7   2.2  
28   1.4   0.7   1.4   4.0   2.8   3.9  
Healthy donors        
1   0.9   0.8   0.2   1.9   0.8   1.6  
2   1.3   1.2   0.3   1.2   0.6   1.2  
3   3.1   2.8   0.7   0.9   0.6   0.8  
4   2.9   2.2   0.6   0.6   0.2   0.5  
5   0.8   0.6   0.1   0.5   0.2   0.5  
6   1.4   1.0   0.3   2.3   0.9   2.1  
7   2.6   2.2   0.6   0.8   0.2   0.6  
8   2.0   1.9   0.2   0.2   0.1   0.1  
9   2.3   2.0   0.3   2.2   1.0   2.1  
10   1.6   1.2   0.9   2.0   0.9   1.9  
11   2.8   2.0   0.3   0.8   0.4   0.7  
12   1.7   1.3   0.2   1.8   1.0   1.7  
13   1.8   1.0   1.1   1.7   0.9   0.6  
14   1.9   1.8   0.5   1.1   0.5   0.9  
15
 
2.4
 
1.6
 
0.2
 
0.4
 
0.2
 
0.4
 



Vδ2+

Vδ2+ CXCR3+

Vδ2+ CXCR4+

Vδ1+

Vδ1+ CXCR3+

Vδ1+ CXCR4+
Patients        
1   1.0   0.9   0.9   1.0   0.8   1.0  
2   1.6   1.5   1.6   1.2   1.0   1.2  
3   0.7   0.6   0.7   1.4   1.3   1.2  
4   1.9   1.8   1.7   2.2   1.8   2.0  
5   0.7   0.7   0.7   4.2   3.2   3.6  
6   2.7   2.8   2.3   4.1   2.0   3.9  
7   0.3   0.2   0.3   1.0   0.9   1.1  
8   3.8   2.8   3.1   2.2   1.6   1.8  
9   0.4   0.3   0.4   2.3   2.0   1.9  
10   2.4   2.3   2.6   2.9   1.9   2.9  
11   0.3   0.2   0.3   8.8   4.3   8.6  
12   1.3   1.3   1.2   2.7   1.7   1.4  
13   1.1   1.0   1.3   2.3   1.6   2.0  
14   3.0   1.9   1.6   1.2   1.0   1.2  
15   1.0   0.9   0.7   2.2   1.3   2.2  
16   3.2   2.4   2.0   4.1   2.3   3.9  
17   3.5   2.2   1.0   4.2   2.0   1.7  
18   4.0   3.3   1.1   9.2   2.9   4.8  
19   2.0   1.9   1.0   0.9   0.6   0.4  
20   1.8   1.4   1.3   4.4   3.3   3.3  
21   3.4   2.9   2.6   9.3   7.3   6.4  
22   1.4   1.4   1.6   2.7   1.7   2.7  
23   0.4   0.2   0.2   2.0   0.8   0.6  
24   4.8   3.8   4.8   3.0   2.9   2.0  
25   3.3   2.5   3.2   1.8   1.5   1.7  
26   2.2   0.8   0.4   3.6   1.2   0.7  
27   2.0   2.0   2.2   2.7   1.7   2.2  
28   1.4   0.7   1.4   4.0   2.8   3.9  
Healthy donors        
1   0.9   0.8   0.2   1.9   0.8   1.6  
2   1.3   1.2   0.3   1.2   0.6   1.2  
3   3.1   2.8   0.7   0.9   0.6   0.8  
4   2.9   2.2   0.6   0.6   0.2   0.5  
5   0.8   0.6   0.1   0.5   0.2   0.5  
6   1.4   1.0   0.3   2.3   0.9   2.1  
7   2.6   2.2   0.6   0.8   0.2   0.6  
8   2.0   1.9   0.2   0.2   0.1   0.1  
9   2.3   2.0   0.3   2.2   1.0   2.1  
10   1.6   1.2   0.9   2.0   0.9   1.9  
11   2.8   2.0   0.3   0.8   0.4   0.7  
12   1.7   1.3   0.2   1.8   1.0   1.7  
13   1.8   1.0   1.1   1.7   0.9   0.6  
14   1.9   1.8   0.5   1.1   0.5   0.9  
15
 
2.4
 
1.6
 
0.2
 
0.4
 
0.2
 
0.4
 

Direct immunofluorescence on whole blood of HIV-1-infected patients was performed with PE-anti-CXCR3 or -CXCR4 mAbs, and the anti-Vδ1 A13 or the anti-Vδ2 BB3 mAbs were labeled using the Zenon Alexafluor 488 mouse IgG1 Labeling Kit. Samples were analyzed on a flow cytometer equipped with an argon ion laser exciting PE and Alexafluor at 488 nm and gated on lymphocytes. Data are expressed as percentage of positive or double-positive cells.

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