PTPN11 mutations detected in myeloid malignancies
Nucleotide . | Substitution . | Amino acid . | Diagnosis . |
|---|---|---|---|
| 179 | G>C | Gly60Ala | AML |
| 181 | G>T | Asp61Tyr | AML |
| 182 | A>T | Asp61Val | MDS |
| 188 | A>G | Tyr63Cys | CMML |
| 211 | T>C | Phe71Lys | t-MDS |
| 215 | C>T | Ala72Val | AML(1) MDS (1) |
| 226 | G>A | Glu76Lys | AML |
| 227 | A>G | Glu76Gly | AML |
Nucleotide . | Substitution . | Amino acid . | Diagnosis . |
|---|---|---|---|
| 179 | G>C | Gly60Ala | AML |
| 181 | G>T | Asp61Tyr | AML |
| 182 | A>T | Asp61Val | MDS |
| 188 | A>G | Tyr63Cys | CMML |
| 211 | T>C | Phe71Lys | t-MDS |
| 215 | C>T | Ala72Val | AML(1) MDS (1) |
| 226 | G>A | Glu76Lys | AML |
| 227 | A>G | Glu76Gly | AML |