Phenotypic correlations among fibrinogen, FXIII activity and subunit levels, and fibrin structure/function parameters
. | Fibrinogen . | Ks . | Maximum absorbance . | FXIII activity . | FXIII A subunit . | FXIII B subunit . |
|---|---|---|---|---|---|---|
| Fibrinogen | 1.00 | — | — | — | — | — |
| Ks | -0.37* (-0.16/-0.21) | 1.00 | — | — | — | — |
| Maximum absorbance | 0.66* (0.24/0.42) | -0.29* (all rE) | 1.00 | — | — | — |
| FXIII activity | 0.12 (NS) | -0.17 (NS) | 0.01 (NS) | 1.00 | — | — |
| FXIII A subunit | 0.22* (all rE) | -0.10 (NS) | 0.19* (all rE) | 0.29* (0.21/0.08) | 1.00 | — |
| FXIII B subunit | 0.40* (0.23/0.17) | -0.22* (all rG) | 0.34* (0.19/0.15) | 0.24* (all rG) | 0.66* (0.51/0.15) | 1.00 |
. | Fibrinogen . | Ks . | Maximum absorbance . | FXIII activity . | FXIII A subunit . | FXIII B subunit . |
|---|---|---|---|---|---|---|
| Fibrinogen | 1.00 | — | — | — | — | — |
| Ks | -0.37* (-0.16/-0.21) | 1.00 | — | — | — | — |
| Maximum absorbance | 0.66* (0.24/0.42) | -0.29* (all rE) | 1.00 | — | — | — |
| FXIII activity | 0.12 (NS) | -0.17 (NS) | 0.01 (NS) | 1.00 | — | — |
| FXIII A subunit | 0.22* (all rE) | -0.10 (NS) | 0.19* (all rE) | 0.29* (0.21/0.08) | 1.00 | — |
| FXIII B subunit | 0.40* (0.23/0.17) | -0.22* (all rG) | 0.34* (0.19/0.15) | 0.24* (all rG) | 0.66* (0.51/0.15) | 1.00 |
Multivariate analysis and path tracing rules were used to quantify the extent to which genetic (G) and environmental (E) factors contribute to the phenotypic correlations (G/E).
Significant at P < .05.