Mutation patterns of the PAX5, RhoH/TTF, c-MYC, and PIM1 genes
Gene . | All mutations . | del/ins . | A . | T . | G . | C . | TS . | TV . | RGYW WRCY . |
|---|---|---|---|---|---|---|---|---|---|
| PAX5 (%) | 65 (100) | 3 (5) | 3 (5) | 1 (2) | 35 (53) | 23 (35) | 39 (60) | 23 (35) | 22 (34) |
| RhoH/TTF (%) | 25 (100) | 0 (0) | 0 (0) | 4 (16) | 14 (56) | 7 (28) | 16 (64) | 9 (36) | 14 (56) |
| c-MYC (%) | 16 (100) | 0 (0) | 0 (0) | 1 (6) | 7 (44) | 8 (50) | 8 (50) | 8 (50) | 4 (25) |
| PIM1 (%) | 19 (100) | 0 (0) | 1 (5) | 1 (5) | 9 (47) | 8 (43) | 9 (47) | 10 (53) | 7 (37) |
| Σ (%) | 125 (100) | 3 (2) | 4 (3) | 7 (6) | 65 (52) | 46 (37) | 72 (58) | 50 (40) | 47 (38) |
Gene . | All mutations . | del/ins . | A . | T . | G . | C . | TS . | TV . | RGYW WRCY . |
|---|---|---|---|---|---|---|---|---|---|
| PAX5 (%) | 65 (100) | 3 (5) | 3 (5) | 1 (2) | 35 (53) | 23 (35) | 39 (60) | 23 (35) | 22 (34) |
| RhoH/TTF (%) | 25 (100) | 0 (0) | 0 (0) | 4 (16) | 14 (56) | 7 (28) | 16 (64) | 9 (36) | 14 (56) |
| c-MYC (%) | 16 (100) | 0 (0) | 0 (0) | 1 (6) | 7 (44) | 8 (50) | 8 (50) | 8 (50) | 4 (25) |
| PIM1 (%) | 19 (100) | 0 (0) | 1 (5) | 1 (5) | 9 (47) | 8 (43) | 9 (47) | 10 (53) | 7 (37) |
| Σ (%) | 125 (100) | 3 (2) | 4 (3) | 7 (6) | 65 (52) | 46 (37) | 72 (58) | 50 (40) | 47 (38) |
del/ins indicates number of deletions and insertions; A, mutations occurring at adenosine position; T, analogous to A; G, analogous to A; C, analogous to A; RGYW/WRCY, number of mutations embedded in the mutational hot spot motive RGYW (R = A, G; Y = C, T; W = A, T); TS, transitions; TV, transversions; and Σ, the sum of the mutations in the respective column.