Table 1.

Patient, donor, and transplantation characteristics, N = 96


Characteristic

Value
Age, y, median (SD)   19.4 (12.6)  
Sex, male/female, no.   53/43  
Primary disease, no.  
    Hematologic malignancy   50  
        Acute leukemia   26  
        Chronic myelogenous leukemia   23  
        Myeloma   1  
    Aplastic anemia   40  
    Other diagnoses*  6  
Donor type, no.  
    HLA-identical sibling   82  
    Unrelated   14  
Conditioning regimen, no.  
    TBI containing   79  
        Cyclophosphamide plus TBI with or without other drug   77  
        Other   2  
    Non-TBI containing   17  
        Cyclophosphamide alone   11  
        Busulfan plus cyclophosphamide   6  
GVHD prophylaxis, no.  
    Cyclosporine alone   25  
    Methotrexate alone   14  
    Cyclosporine plus methotrexate with or without other drug   47  
    Cyclosporine with or without prednisone   3  
    Other regimen   3  
    None  4  
HCV genotype, no.  
    Type 1   35  
    Type 2   14  
    Type 3   12  
    Type 4
 
4
 

Characteristic

Value
Age, y, median (SD)   19.4 (12.6)  
Sex, male/female, no.   53/43  
Primary disease, no.  
    Hematologic malignancy   50  
        Acute leukemia   26  
        Chronic myelogenous leukemia   23  
        Myeloma   1  
    Aplastic anemia   40  
    Other diagnoses*  6  
Donor type, no.  
    HLA-identical sibling   82  
    Unrelated   14  
Conditioning regimen, no.  
    TBI containing   79  
        Cyclophosphamide plus TBI with or without other drug   77  
        Other   2  
    Non-TBI containing   17  
        Cyclophosphamide alone   11  
        Busulfan plus cyclophosphamide   6  
GVHD prophylaxis, no.  
    Cyclosporine alone   25  
    Methotrexate alone   14  
    Cyclosporine plus methotrexate with or without other drug   47  
    Cyclosporine with or without prednisone   3  
    Other regimen   3  
    None  4  
HCV genotype, no.  
    Type 1   35  
    Type 2   14  
    Type 3   12  
    Type 4
 
4
 

SD indicates standard deviation; HLA, human leukocyte antigen; and TBI, total body irradiation.

*

Thalassemia (n = 2), Glanzmann thrombasthenia, Diamond-Blackfan syndrome (n = 2), dyskeratosis congenital.

Transplantation in which the donor and recipient were twins.

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