Table 3.

Multivariate analysis of factors that predicted severe complications in the entire population (MM and other cancers) (n = 190)


Variable

No. of patients with complication (%); total = 36

No. of patients without complication (%); total = 154

P

Odds ratio (95% CI)
Before therapy     
    Renal failure   20 (56)   26 (17)   .0001   8.3 (2.9-23.7)  
    LDH*  15 (42)   34 (22)   .017   3.4 (1.3-9.5)  
After therapy     
    No mucositis   6 (17)   68 (47)   .029   1  
    Mucositis grade I/II   13 (37)   48 (33)   .013   5.7 (1.4-22.3)  
    Mucositis grade III/IV
 
16 (46)
 
30 (21)
 
.020
 
5.2 (1.3-20.6)
 

Variable

No. of patients with complication (%); total = 36

No. of patients without complication (%); total = 154

P

Odds ratio (95% CI)
Before therapy     
    Renal failure   20 (56)   26 (17)   .0001   8.3 (2.9-23.7)  
    LDH*  15 (42)   34 (22)   .017   3.4 (1.3-9.5)  
After therapy     
    No mucositis   6 (17)   68 (47)   .029   1  
    Mucositis grade I/II   13 (37)   48 (33)   .013   5.7 (1.4-22.3)  
    Mucositis grade III/IV
 
16 (46)
 
30 (21)
 
.020
 
5.2 (1.3-20.6)
 
*

Increased serum LDH (> 190 IU/L).

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