Multivariate analysis of factors that predicted severe complications in patients with multiple myeloma (n = 147)
Variable . | No. of patients with complication (%); total = 29 . | No. of patients without complication (%); total = 118 . | P . | Odds ratio (95% CI) . |
|---|---|---|---|---|
| Before therapy | ||||
| Renal failure | 17 (59) | 22 (19) | .0004 | 10.2 (2.8-36.8) |
| LDH* | 14 (48) | 21 (18) | .0008 | 9.2 (2.5-33.7) |
| After therapy | ||||
| No mucositis | 6 (21) | 61 (52) | .046 | 1 |
| Mucositis grade I/II | 9 (31) | 34 (29) | .029 | 5.9 (1.2-29) |
| Mucositis grade III/IV | 14 (48) | 23 (20) | .024 | 6.2 (2.5-33.7) |
Variable . | No. of patients with complication (%); total = 29 . | No. of patients without complication (%); total = 118 . | P . | Odds ratio (95% CI) . |
|---|---|---|---|---|
| Before therapy | ||||
| Renal failure | 17 (59) | 22 (19) | .0004 | 10.2 (2.8-36.8) |
| LDH* | 14 (48) | 21 (18) | .0008 | 9.2 (2.5-33.7) |
| After therapy | ||||
| No mucositis | 6 (21) | 61 (52) | .046 | 1 |
| Mucositis grade I/II | 9 (31) | 34 (29) | .029 | 5.9 (1.2-29) |
| Mucositis grade III/IV | 14 (48) | 23 (20) | .024 | 6.2 (2.5-33.7) |
Increased serum LDH (> 190 IU/L).