Comparison of donor myeloid and T-cell chimerism in patients with or without a history of prior chemotherapy exposure
Lineage and day after transplantation . | Prior chemotherapy, n = 18; % donor chimerism median (range) . | No prior chemotherapy, n = 18; % donor chimerism median (range) . | P, Wilcoxon rank sum test . |
|---|---|---|---|
| Myeloid day 15 | 52 (19-94) | 8 (1-86) | .0003 |
| Myeloid day 30 | 76 (24-97) | 26 (5-58) | < .0001 |
| Myeloid day 45 | 73 (19-99) | 25 (5-82) | .0005 |
| Myeloid day 60 | 84 (15-100) | 24 (0-100) | .005 |
| Myeloid day 100 | 100 (18-100) | 50 (0-100) | .053 |
| T-cell day 15 | 96 (55-100) | 93 (71-100) | .25 |
| T-cell day 30 | 98 (81-100) | 88 (55-100) | .008 |
| T-cell day 45 | 98 (88-100) | 93 (66-100) | .012 |
| T-cell day 60 | 100 (89-100) | 95 (85-100) | .042 |
| T-cell day 100 | 100 (85-100) | 98 (75-100) | .045 |
Lineage and day after transplantation . | Prior chemotherapy, n = 18; % donor chimerism median (range) . | No prior chemotherapy, n = 18; % donor chimerism median (range) . | P, Wilcoxon rank sum test . |
|---|---|---|---|
| Myeloid day 15 | 52 (19-94) | 8 (1-86) | .0003 |
| Myeloid day 30 | 76 (24-97) | 26 (5-58) | < .0001 |
| Myeloid day 45 | 73 (19-99) | 25 (5-82) | .0005 |
| Myeloid day 60 | 84 (15-100) | 24 (0-100) | .005 |
| Myeloid day 100 | 100 (18-100) | 50 (0-100) | .053 |
| T-cell day 15 | 96 (55-100) | 93 (71-100) | .25 |
| T-cell day 30 | 98 (81-100) | 88 (55-100) | .008 |
| T-cell day 45 | 98 (88-100) | 93 (66-100) | .012 |
| T-cell day 60 | 100 (89-100) | 95 (85-100) | .042 |
| T-cell day 100 | 100 (85-100) | 98 (75-100) | .045 |