Table 1. Summary of TgN(csCSF1)Ers1-10... | American Society of Hematology

Table 1.

Summary of TgN(csCSF1)Ers1-10 (TgCS1-10) mouse lines

			*Transmissibility to Csf1^op/Csf1^op* background**	Serum CSF-1 level	*Correction of gross phenotype of Csf1^op/Csf1^op* mice**
Founder	Background	Transmissibility^*	*Transmissibility to Csf1^op/Csf1^op* background**	Serum CSF-1 level			Osteopetrosis	Tooth eruption	Growth rate	Reproductive function
TgCS1†	OB	T	T	ND	PC	CC	CC	CC
TgCS2	FVB/NJ	NT	—	—	—	—	—	—
TgCS3	FVB/NJ	NT	—	—	—	—	—	—
TgCS4	FVB/NJ	T	NT	—	—	—	—	—
TgCS5	OB	T	T	ND	PC	CC	CC	CC
	FVB/NJ	T	T	ND	PC	CC	CC	CC
TgCS6	FVB/NJ	NT	—	—	—	—	—	—
TgCS7	FVB/NJ	NT	—	—	—	—	—	—
TgCS8	FVB/NJ	T	T	ND	PC	CC	CC	CC
TgCS9	FVB/NJ	T	T	ND	PC	CC	CC	CC
TgCS10	FVB/NJ	T	T	ND	PC	CC	CC	CC

			*Transmissibility to Csf1^op/Csf1^op* background**	Serum CSF-1 level	*Correction of gross phenotype of Csf1^op/Csf1^op* mice**
Founder	Background	Transmissibility^*	*Transmissibility to Csf1^op/Csf1^op* background**	Serum CSF-1 level			Osteopetrosis	Tooth eruption	Growth rate	Reproductive function
TgCS1†	OB	T	T	ND	PC	CC	CC	CC
TgCS2	FVB/NJ	NT	—	—	—	—	—	—
TgCS3	FVB/NJ	NT	—	—	—	—	—	—
TgCS4	FVB/NJ	T	NT	—	—	—	—	—
TgCS5	OB	T	T	ND	PC	CC	CC	CC
	FVB/NJ	T	T	ND	PC	CC	CC	CC
TgCS6	FVB/NJ	NT	—	—	—	—	—	—
TgCS7	FVB/NJ	NT	—	—	—	—	—	—
TgCS8	FVB/NJ	T	T	ND	PC	CC	CC	CC
TgCS9	FVB/NJ	T	T	ND	PC	CC	CC	CC
TgCS10	FVB/NJ	T	T	ND	PC	CC	CC	CC

OB indicates outbred; T, transmissible; ND, not detectable; PC, partially corrected; CC, completely corrected; NT, nontransmissible; —, not done or not applicable.

The transmission of transgene to the next generation.

†

Lost line.

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