ES/OP9-derived neutrophils display similar migratory behavior as mouse bone marrow-derived PMNs
. | . | Migratory rate, μm/min . | . | . | ||
|---|---|---|---|---|---|---|
| Cells . | % of total . | Mean . | Peak . | MI . | ||
| Unresponsive BM PMNs | 41.7 ± 11 | NA | NA | NA | ||
| Unresponsive ES PMNs | 18.7 ± 13 | NA | NA | NA | ||
| NDM BM PMNs | 19.4 ± 14.4 | 6.1 ± 4.6 | 11.6 ± 6.8 | -.1 | ||
| NDM ES PMNs | 30.3 ± 17.2 | 10.4 ± 7.8 | 16.8 ± 11.4 | .03 | ||
| Chemotactic BM PMNs | 38.7 ± 12.1 | 8.1 ± 5.1 | 14.5 ± 6.5 | .85 | ||
| Chemotactic ES PMNs | 50.6 ± 16.4 | 11.9 ± 7.2 | 16.6 ± 9.3 | .84 | ||
. | . | Migratory rate, μm/min . | . | . | ||
|---|---|---|---|---|---|---|
| Cells . | % of total . | Mean . | Peak . | MI . | ||
| Unresponsive BM PMNs | 41.7 ± 11 | NA | NA | NA | ||
| Unresponsive ES PMNs | 18.7 ± 13 | NA | NA | NA | ||
| NDM BM PMNs | 19.4 ± 14.4 | 6.1 ± 4.6 | 11.6 ± 6.8 | -.1 | ||
| NDM ES PMNs | 30.3 ± 17.2 | 10.4 ± 7.8 | 16.8 ± 11.4 | .03 | ||
| Chemotactic BM PMNs | 38.7 ± 12.1 | 8.1 ± 5.1 | 14.5 ± 6.5 | .85 | ||
| Chemotactic ES PMNs | 50.6 ± 16.4 | 11.9 ± 7.2 | 16.6 ± 9.3 | .84 | ||
MI indicates net displacement of cells towards chemoattractant/total path length of cells (a negative MI indicates that the net cell migration was away from the chemoattractant); NDM, nondirectional migration in the presence of a gradient; and NA, not applicable. Data are shown ± standard deviations.