Table 2.

High levels of anti-GM-CSF autoantibodies in iPAP patients


Sample

iPAP median, μg/mL

Healthy control*median, μg/mL

Other lung disorders*median, μg/mL
BALF   1.15 (0.094-5.40), n = 34   < 0.050, n = 18   < 0.050, n = 14  
Serum
 
88.6 (16.6-470), n = 107
 
< 3.00, n = 19
 
< 3.00, n = 10
 

Sample

iPAP median, μg/mL

Healthy control*median, μg/mL

Other lung disorders*median, μg/mL
BALF   1.15 (0.094-5.40), n = 34   < 0.050, n = 18   < 0.050, n = 14  
Serum
 
88.6 (16.6-470), n = 107
 
< 3.00, n = 19
 
< 3.00, n = 10
 

Numbers in parentheses are ranges.

*

Concentrations of autoantibodies in BALF and serum were all under the detection limit (0.05 μg/mL in BALF; 3 μg/mL in serum).

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