Table 2.

Hematologic parameters in humans with HS


ID number (age)

Hemoglobin, g/L

MCHC, g/dL

Reticulocytes, %

Splenectomy, yes/no
HS1 (8 y)   104   34.4   10.7   No  
HS2 (10 y)   99   36.2   15.9   No  
HS3 (11 y)   131   35.8   4.3   No  
HS4 (4 y)   131   35.8   14.5   No  
HS5 (adult)   169   37.0   3.3   Yes  
HS6 (5 y)   124   34.6   4.1   No  
HS7 (2 y)   90   36.3   12.7   No  
HS8 (4 y)   88   36.4   18.1   No  
HA (16 y)   55   33.5   21.1   Yes  
Normal
 
115-150
 
32.0-36.0
 
<2.2
 
NA
 

ID number (age)

Hemoglobin, g/L

MCHC, g/dL

Reticulocytes, %

Splenectomy, yes/no
HS1 (8 y)   104   34.4   10.7   No  
HS2 (10 y)   99   36.2   15.9   No  
HS3 (11 y)   131   35.8   4.3   No  
HS4 (4 y)   131   35.8   14.5   No  
HS5 (adult)   169   37.0   3.3   Yes  
HS6 (5 y)   124   34.6   4.1   No  
HS7 (2 y)   90   36.3   12.7   No  
HS8 (4 y)   88   36.4   18.1   No  
HA (16 y)   55   33.5   21.1   Yes  
Normal
 
115-150
 
32.0-36.0
 
<2.2
 
NA
 

HS3 and HS4 are half-siblings. HS5 and HS6 are father and daughter. HS7 and HS8 are siblings. HA has a nonspherocytic hemolytic anemia of unknown etiology.

MCHC indicates mean corpuscular hemoglobin concentration; ND, not done; and NA, not applicable.

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