Physiologic measurements in apoE-/- → apoE-/- and p27-/- apoE-/- → apoE-/- mice
. | . | Plasma cholesterol (mg/dL) . | . | Transplant donor engraftment (%) . | . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| Bone marrow donor genotype . | Weight (g) . | Before diet . | After diet . | Bone marrow . | Spleen . | Thymus . | |||
| apoE-/- → apoE-/- | 19.6 ± 0.6 (n = 15) | 336 ± 35 (n = 15) | 2733 ± 266 (n = 15) | 43 ± 4 (n = 5) | 49 ± 5 (n = 5) | 48 ± 3 (n = 5) | |||
| p27-/- apoE-/- → apoE-/- | 20.4 ± 0.8 (n = 15) | 363 ± 21 (n = 15) | 2626 ± 109 (n = 15) | 44 ± 9 (n = 4) | 87 ± 5 (n = 4)* | 67 ± 6 (n = 4) | |||
. | . | Plasma cholesterol (mg/dL) . | . | Transplant donor engraftment (%) . | . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| Bone marrow donor genotype . | Weight (g) . | Before diet . | After diet . | Bone marrow . | Spleen . | Thymus . | |||
| apoE-/- → apoE-/- | 19.6 ± 0.6 (n = 15) | 336 ± 35 (n = 15) | 2733 ± 266 (n = 15) | 43 ± 4 (n = 5) | 49 ± 5 (n = 5) | 48 ± 3 (n = 5) | |||
| p27-/- apoE-/- → apoE-/- | 20.4 ± 0.8 (n = 15) | 363 ± 21 (n = 15) | 2626 ± 109 (n = 15) | 44 ± 9 (n = 4) | 87 ± 5 (n = 4)* | 67 ± 6 (n = 4) | |||
With the exception of prediet plasma cholesterol, all parameters were measured after mice had been killed. Results were compared by 2-tailed, unpaired, Student t test. Only statistically significant differences are shown (P < .05). Results are shown as mean ± SE.
P < .002.