Table 1.

Patient characteristics


Age, y 

 
    Median   53  
    Range   1-72  
Sex, no. (%)  
    Male   116 (60)  
    Female   77 (40)  
Conditioning regimen, no. (%)  
    TBI, 2 Gy   48 (25)  
    Flu/TBI, 2 Gy   142 (74)  
    None   3  
Donors, no. (%)  
    Related   145 (75)  
    Unrelated   48 (25)  
Diseases, no.  
    Hematologic malignancies   168  
        Multiple myeloma   36  
        MDS, MDS/AML   28  
        AML   18  
        NHL, low grade   5  
        NHL, intermediate/high grade   22  
        CLL   19  
        CML   15  
        HD   14  
        ALL   8  
        Waldenström macroglobulinemia   3  
    Renal cell carcinoma   8  
    Immunodeficiency disorders   7  
    Other   10  
Disease risk*, no.   
    Indolent   81  
    Aggressive
 
102
 

Age, y 

 
    Median   53  
    Range   1-72  
Sex, no. (%)  
    Male   116 (60)  
    Female   77 (40)  
Conditioning regimen, no. (%)  
    TBI, 2 Gy   48 (25)  
    Flu/TBI, 2 Gy   142 (74)  
    None   3  
Donors, no. (%)  
    Related   145 (75)  
    Unrelated   48 (25)  
Diseases, no.  
    Hematologic malignancies   168  
        Multiple myeloma   36  
        MDS, MDS/AML   28  
        AML   18  
        NHL, low grade   5  
        NHL, intermediate/high grade   22  
        CLL   19  
        CML   15  
        HD   14  
        ALL   8  
        Waldenström macroglobulinemia   3  
    Renal cell carcinoma   8  
    Immunodeficiency disorders   7  
    Other   10  
Disease risk*, no.   
    Indolent   81  
    Aggressive
 
102
 

Flu indicates fludarabine; MDS, myelodysplastic syndrome; AML, acute myeloid leukemia; NHL, non-Hodgkin lymphoma; CLL, chronic lymphocytic leukemia; CML, chronic myeloid leukemia; HD, Hodgkin disease; and ALL, acute lymphocytic leukemia.

“Indolent” hematologic malignancies included CML in first complete remission (CR), AML in first CR, Philadelphia chromosome (Ph)—negative ALL in first CR, MDS refractory anemia (RA) with or without ringed sideroblasts (RS), myeloma in CR/partial remission (PR), aggressive NHL in first CR, HD in first CR, low-grade NHL and CLL.

“Aggressive” malignancies included renal cell carcinoma, other solid organ tumors, CML in accelerated phase (AP) or greater than CR1, AML beyond first CR, ALL beyond first CR, Ph-positive ALL in first CR, MDS other than RA (RS), multiple myeloma not in CR/PR, HD beyond first CR, and other NHL.

*

Disease risk only refers to malignant diseases.

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