Table 2.

Fib+/-: Par4-/- intercross: no. alive at E18.5


Genotype  

Fib+/+: Par4-/- 

Fib+/-: Par4-/- 

Fib-/-: Par4-/- 
Observed   34   55   30  
Expected
 
29.75
 
59.5
 
29.75
 

Genotype  

Fib+/+: Par4-/- 

Fib+/-: Par4-/- 

Fib-/-: Par4-/- 
Observed   34   55   30  
Expected
 
29.75
 
59.5
 
29.75
 

Embryos from the indicated cross were collected at E18.5, scored as alive or dead based on the presence or absence of a heartbeat, and genotyped. Note that 31 Fib-/-: Par4-/- embryos were collected and 30 were alive. Of these 30 embryos, 28 appeared to be normal and were indistinguishable from their littermates. Two embryos were alive but showed intra-abdominal bleeding.

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