First-line treatments and outcome
| . | Induction phase . | . | Consolidation phase . | . | . | . | . | ||
|---|---|---|---|---|---|---|---|---|---|
| Patient . | Regimen . | Response . | Regimen . | Response . | Relapse, mo . | Survival, mo . | Status . | ||
| 1spl | CHOP | CR | Chemotherapy | CR | 16 | 37 | DOD | ||
| 2spl | CHOP-like | CR | Chemotherapy | CR | 16 | 44 | DOD | ||
| 3spl | CHOP-like | CR | Auto BMT | CR | 8 | 24 | DOD | ||
| 4spl | CHOP-like | CR | Auto BMT | CR | 15 | 33 | DOD | ||
| 5spl | CHOP-like | CR | Chemotherapy | CR | 13 | 36 | DOD | ||
| 6spl | CHOP-like | CR | Allo BMT | CR | 15 | 25 | DOD | ||
| 7 | CHOP-like | PR | Auto PBSC | CR | 4† | 19 | DOD | ||
| 8 | CHOP-like | PR | Auto PBSC | Failure | — | 13 | DOD | ||
| 9 | CHOP-like | CR | Chemotherapy | CR | 3 | 10 | DOD | ||
| 10spl | CHOP-like | Failure | — | — | — | 1 | DOD | ||
| 11 | CHOP | Failure | — | — | — | 6 | DOD | ||
| 12spl | CHOP-like | Failure* | — | — | — | 11 | DOD | ||
| 13spl | CHOP-like | CR | Allo BMT | NE | — | 6 | TRD | ||
| 14spl | CHOP | Failure | — | — | — | 1 | DOD | ||
| 15spl | CHOP-like | CR | Chemotherapy | CR | 3* | 33 | DOD | ||
| 16 | CHOP-like | PR | Allo BMT | NE | — | 9 | TRD | ||
| 17 | Platinum-Ara-C based | PR | Auto PBSC | CR | — | 52 | Alive | ||
| 18 | CHOP | Failure | — | — | — | 2 | DOD | ||
| 19spl | Platinum-Ara-C based | PR | Auto PBSC | CR | — | 42 | Alive | ||
| 20 | CHOP-like | Failure | — | — | — | 16 | DOD | ||
| 21 | CHOP-like | Failure | — | — | — | 7 | DOD | ||
| . | Induction phase . | . | Consolidation phase . | . | . | . | . | ||
|---|---|---|---|---|---|---|---|---|---|
| Patient . | Regimen . | Response . | Regimen . | Response . | Relapse, mo . | Survival, mo . | Status . | ||
| 1spl | CHOP | CR | Chemotherapy | CR | 16 | 37 | DOD | ||
| 2spl | CHOP-like | CR | Chemotherapy | CR | 16 | 44 | DOD | ||
| 3spl | CHOP-like | CR | Auto BMT | CR | 8 | 24 | DOD | ||
| 4spl | CHOP-like | CR | Auto BMT | CR | 15 | 33 | DOD | ||
| 5spl | CHOP-like | CR | Chemotherapy | CR | 13 | 36 | DOD | ||
| 6spl | CHOP-like | CR | Allo BMT | CR | 15 | 25 | DOD | ||
| 7 | CHOP-like | PR | Auto PBSC | CR | 4† | 19 | DOD | ||
| 8 | CHOP-like | PR | Auto PBSC | Failure | — | 13 | DOD | ||
| 9 | CHOP-like | CR | Chemotherapy | CR | 3 | 10 | DOD | ||
| 10spl | CHOP-like | Failure | — | — | — | 1 | DOD | ||
| 11 | CHOP | Failure | — | — | — | 6 | DOD | ||
| 12spl | CHOP-like | Failure* | — | — | — | 11 | DOD | ||
| 13spl | CHOP-like | CR | Allo BMT | NE | — | 6 | TRD | ||
| 14spl | CHOP | Failure | — | — | — | 1 | DOD | ||
| 15spl | CHOP-like | CR | Chemotherapy | CR | 3* | 33 | DOD | ||
| 16 | CHOP-like | PR | Allo BMT | NE | — | 9 | TRD | ||
| 17 | Platinum-Ara-C based | PR | Auto PBSC | CR | — | 52 | Alive | ||
| 18 | CHOP | Failure | — | — | — | 2 | DOD | ||
| 19spl | Platinum-Ara-C based | PR | Auto PBSC | CR | — | 42 | Alive | ||
| 20 | CHOP-like | Failure | — | — | — | 16 | DOD | ||
| 21 | CHOP-like | Failure | — | — | — | 7 | DOD | ||
Relapse values represent time from end of first-line treatment. Survival values represent time from diagnosis. CR indicates complete response; DOD, died of disease; BMT, bone marrow transplantation; PR, good partial response; PBSC, peripheral blood stem cell; —, not applicable; NE, nonevaluable because of cerebral toxoplasmosis; TRD, transplantation-related death; and spl, splenectomy. *Salvage treatment by autotransplantation. †Salvage treatment by allotransplantation.