Table 2.

Characteristics of 14 patients with CML before SCT



Disease stage at analysis

BCR-ABL translocation

Time from diagnosis to analysis, mo


T-cell response
UPN
Treatment
PR1
WT1
BCR-ABL
16   CML-CP   b3a2   2   HU   N   N   N  
17   CML-CP   NA   4   BU, HU   Y   Y   ND  
25   CML-CP   NA   15   BU   N   Y   ND  
38   CML-CP   NA   3   HU   Y   Y   ND  
41   CML-CP   b3a2   24   HU   Y   Y   N  
181   CML-CP   b3a2   2   HU, IFN-α   Y   N   N  
199   CML-CP   b2a2   15   HU   Y   Y   ND  
210   CML-LBC, 2nd CP   b2a2   4   HU, IFN-α, hyper CVAD-3 cycles   Y   Y   Y  
241   CML-CP   b3a2   3   HU   N   N   N  
254   CML-CP   NA   8   HU   Y   Y   Y  
262   CML-CP   b3a2/b2a2   5   HU   N   N   N  
283   CML-MBC, 2nd CP   b3a2/b2a2   84   HU, imatinib mesylate   Y   N   Y  
319   CML-CP   b3a2   4   HU, anagrelide   N   N   N  
327
 
CML-CP
 
b3a2
 
9
 
HU, Ara-C
 
N
 
N
 
ND
 


Disease stage at analysis

BCR-ABL translocation

Time from diagnosis to analysis, mo


T-cell response
UPN
Treatment
PR1
WT1
BCR-ABL
16   CML-CP   b3a2   2   HU   N   N   N  
17   CML-CP   NA   4   BU, HU   Y   Y   ND  
25   CML-CP   NA   15   BU   N   Y   ND  
38   CML-CP   NA   3   HU   Y   Y   ND  
41   CML-CP   b3a2   24   HU   Y   Y   N  
181   CML-CP   b3a2   2   HU, IFN-α   Y   N   N  
199   CML-CP   b2a2   15   HU   Y   Y   ND  
210   CML-LBC, 2nd CP   b2a2   4   HU, IFN-α, hyper CVAD-3 cycles   Y   Y   Y  
241   CML-CP   b3a2   3   HU   N   N   N  
254   CML-CP   NA   8   HU   Y   Y   Y  
262   CML-CP   b3a2/b2a2   5   HU   N   N   N  
283   CML-MBC, 2nd CP   b3a2/b2a2   84   HU, imatinib mesylate   Y   N   Y  
319   CML-CP   b3a2   4   HU, anagrelide   N   N   N  
327
 
CML-CP
 
b3a2
 
9
 
HU, Ara-C
 
N
 
N
 
ND
 

UPN indicates unique patient number; CML-CP, CML chronic phase; HU, hydroxyurea; NA, not available; BU, busulphan; IFN-α, interferon-α; CML-LBC, CML lymphoid blast crisis; hyper CVAD, cyclophosphamide, doxorubicin, vincristine, and dexamethasone; CML-MBC, CML myeloid blast crisis; Ara-C, cytosine-arabinoside; and ND, not done.

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