Frequency and molecular profile of BCL-6 mutations in monoclonal B-cell PTLDs
Case . | Histology . | Mutation . |
|---|---|---|
| 2916 | P-PTLD | 449T>C, 645G>C, 823T>A, 978G>A |
| 3519 | P-PTLD | 445C>G, 477T>C, 564T>C, 863A>G |
| 3521 | P-PTLD | 443A>T, 506A>G, 668A>G, 802A>G, 803C>G, 837T>G |
| 2909 | DLBCL, centroblastic | 464T>A, 707T>G, 724T>A, 977A>G, 1102T>G |
| 3459 | DLBCL, centroblastic | 855G>A |
| 3466 | DLBCL, centroblastic | 479G>A |
| 3467 | DLBCL, centroblastic | 453A>C, 459G>C, 506A>C, 692G>C |
| 3518 | DLBCL, centroblastic | 523C>T, 1101T>C |
| 3522 | DLBCL, centroblastic | 802A>G, 831G>C |
| 3523 | DLBCL, centroblastic | 441G>A, 826G>A |
| 3524 | DLBCL, centroblastic | 441G>A |
| 3527 | DLBCL, centroblastic | 680C>G, 876C>T |
| 3528 | DLBCL, centroblastic | 445C>G |
| 2616 | DLBCL, immunoblastic | 1031G>C |
| 2802 | DLBCL, immunoblastic | 863A>G, 1060T>G |
| 2892 | DLBCL, immunoblastic | 479G>C |
| 2895 | DLBCL, immunoblastic | 759G>C, 917C>G, 937T>C |
| 2911 | DLBCL, immunoblastic | 469A>T, 669T>A |
| 2915 | DLBCL, immunoblastic | 480C>G, 837T>G, 975G>A, 1007T>C |
| 3469 | DLBCL, immunoblastic | 820G>C, 821G>T |
| 3476 | DLBCL, immunoblastic | 567T>G, 570T>C, 608C>T, 624T>G, 626T>A, 889Δ17 bp |
| 3520 | DLBCL, immunoblastic | 542A>G, 656G>A, 821G>A, 876C>T, 946C>T, 948T>C, 974G>A, 975G>A, 1052A>C, 1065A>G, 1096T>A |
| 3529 | DLBCL, immunoblastic | 1026T>A |
| 2617 | BL/BLL | 734G>A, 747A>C, 748G>A |
| 3463 | BL/BLL | 476C>G, 496T>C, 519G>C, 537T>A, 635T>C, 702C>G, 724T>C |
| 3526 | BL/BLL | 957A>T |
Case . | Histology . | Mutation . |
|---|---|---|
| 2916 | P-PTLD | 449T>C, 645G>C, 823T>A, 978G>A |
| 3519 | P-PTLD | 445C>G, 477T>C, 564T>C, 863A>G |
| 3521 | P-PTLD | 443A>T, 506A>G, 668A>G, 802A>G, 803C>G, 837T>G |
| 2909 | DLBCL, centroblastic | 464T>A, 707T>G, 724T>A, 977A>G, 1102T>G |
| 3459 | DLBCL, centroblastic | 855G>A |
| 3466 | DLBCL, centroblastic | 479G>A |
| 3467 | DLBCL, centroblastic | 453A>C, 459G>C, 506A>C, 692G>C |
| 3518 | DLBCL, centroblastic | 523C>T, 1101T>C |
| 3522 | DLBCL, centroblastic | 802A>G, 831G>C |
| 3523 | DLBCL, centroblastic | 441G>A, 826G>A |
| 3524 | DLBCL, centroblastic | 441G>A |
| 3527 | DLBCL, centroblastic | 680C>G, 876C>T |
| 3528 | DLBCL, centroblastic | 445C>G |
| 2616 | DLBCL, immunoblastic | 1031G>C |
| 2802 | DLBCL, immunoblastic | 863A>G, 1060T>G |
| 2892 | DLBCL, immunoblastic | 479G>C |
| 2895 | DLBCL, immunoblastic | 759G>C, 917C>G, 937T>C |
| 2911 | DLBCL, immunoblastic | 469A>T, 669T>A |
| 2915 | DLBCL, immunoblastic | 480C>G, 837T>G, 975G>A, 1007T>C |
| 3469 | DLBCL, immunoblastic | 820G>C, 821G>T |
| 3476 | DLBCL, immunoblastic | 567T>G, 570T>C, 608C>T, 624T>G, 626T>A, 889Δ17 bp |
| 3520 | DLBCL, immunoblastic | 542A>G, 656G>A, 821G>A, 876C>T, 946C>T, 948T>C, 974G>A, 975G>A, 1052A>C, 1065A>G, 1096T>A |
| 3529 | DLBCL, immunoblastic | 1026T>A |
| 2617 | BL/BLL | 734G>A, 747A>C, 748G>A |
| 3463 | BL/BLL | 476C>G, 496T>C, 519G>C, 537T>A, 635T>C, 702C>G, 724T>C |
| 3526 | BL/BLL | 957A>T |
P-PTLD indicates polymorphic PTLD; DLBCL, diffuse large B-cell lymphoma; and BL/BLL, Burkitt lymphoma/Burkitt-like lymphoma.