Association of histologic BOOP with acute and chronic raft-versus-host disease after adjustment for other variables in 2 conditional logistic regression models
. | Odds ratio, unadjusted* . | Odds ratio, adjusted† . | 95% CI for adjusted odds ratio† . | . | |
|---|---|---|---|---|---|
| Factor . | . | . | Lower . | Upper . | |
| Acute GVHD model | |||||
| Acute GVHD | 4.4 | 3.8 | 1.2 | 12.3 | |
| Acute GVHD—organ affected | |||||
| Skin | 4.3 | 4.6 | 1.6 | 13.1 | |
| Liver | 1.7 | 1.3 | 0.6 | 3.1 | |
| Gut | 1.8 | 1.3 | 0.5 | 2.9 | |
| Chronic GVHD model | |||||
| Chronic GVHD | 2.6 | 3.1 | 1.1 | 9.2 | |
| Chronic GVHD—organ affected | |||||
| Skin | 1.2 | 1.0 | 0.3 | 3.1 | |
| Liver | 1.0 | 0.9 | 0.2 | 3.1 | |
| Gut | 3.6 | 6.6 | 1.4 | 31.8 | |
| Eye | 1.6 | 2.4 | 0.7 | 8.3 | |
| Oral | 1.9 | 5.9 | 1.2 | 5.9 | |
| Chronic GVHD—classification | |||||
| De novo | 1.3 | 0.9 | 0.2 | 3.5 | |
| Quiescent | 2.3 | 2.0 | 0.7 | 5.4 | |
| Progressive | 4.7 | 3.8 | 1.3 | 10.8 | |
. | Odds ratio, unadjusted* . | Odds ratio, adjusted† . | 95% CI for adjusted odds ratio† . | . | |
|---|---|---|---|---|---|
| Factor . | . | . | Lower . | Upper . | |
| Acute GVHD model | |||||
| Acute GVHD | 4.4 | 3.8 | 1.2 | 12.3 | |
| Acute GVHD—organ affected | |||||
| Skin | 4.3 | 4.6 | 1.6 | 13.1 | |
| Liver | 1.7 | 1.3 | 0.6 | 3.1 | |
| Gut | 1.8 | 1.3 | 0.5 | 2.9 | |
| Chronic GVHD model | |||||
| Chronic GVHD | 2.6 | 3.1 | 1.1 | 9.2 | |
| Chronic GVHD—organ affected | |||||
| Skin | 1.2 | 1.0 | 0.3 | 3.1 | |
| Liver | 1.0 | 0.9 | 0.2 | 3.1 | |
| Gut | 3.6 | 6.6 | 1.4 | 31.8 | |
| Eye | 1.6 | 2.4 | 0.7 | 8.3 | |
| Oral | 1.9 | 5.9 | 1.2 | 5.9 | |
| Chronic GVHD—classification | |||||
| De novo | 1.3 | 0.9 | 0.2 | 3.5 | |
| Quiescent | 2.3 | 2.0 | 0.7 | 5.4 | |
| Progressive | 4.7 | 3.8 | 1.3 | 10.8 | |
Unadjusted, but matching was maintained.
Acute GVHD adjusted for age, year of transplantation, diagnostic group, preparative chemotherapeutic regimen, stem cell source, and stem cell HLA typing in a conditional logistic regression model. Chronic GVHD adjusted for age, year of transplantation, diagnostic group, preparative chemotherapeutic regimen, sex, and GVHD prophylaxis with steroids in a conditional logistic regression model.