Multivariate model predicting a first spontaneous abortion between 8 and 10 weeks of pregnancy
Biomarkers . | Adjusted odds ratio* . | 95% confidence interval . | P† . |
|---|---|---|---|
| Lupus anticoagulant, positive | 2.6 | 1.1-6.0 | .025 |
| Anticardiolipin IgM, MPL units | <.001 | ||
| 0.8-8.0 | 1.0 | Reference | |
| 8.1-11.0 | 1.7 | 1.1-2.6 | |
| 11.3-17.0 | 1.9 | 0.9-4.0 | |
| Greater than 17.0 | 3.5 | 1.2-10.1 | |
| Antiphosphatidylethanolamine IgM‡ | .001 | ||
| 0-0.267 | 1.0 | Reference | |
| 0.268-0.450 | 1.3 | 0.9-1.9 | |
| 0.453-0.539 | 1.4 | 0.7-3.0 | |
| Greater than 0.539 | 4.7 | 1.9-12.1 | |
| Anti-annexin V IgG‡ | .005 | ||
| 0.030-0.165 | 1.0 | Reference | |
| 0.166-0.263 | 1.4 | 1.0-2.1 | |
| 0.265-0.366 | 1.3 | 0.6-2.7 | |
| Greater than 0.366 | 3.2 | 1.1-9.1 | |
| Antitissue type plasminogen activator IgG† | <.001 | ||
| 0.0.087 | 1.0 | Reference | |
| 0.088-0.157 | 8.5 | 5.9-12.1 | |
| 0.159-0.259 | 8.1 | 4.7-14.1 | |
| Greater than 0.259 | 19.5 | 7.9-48.0 | |
| Plasma homocysteine, μM | <.001 | ||
| 3.4-9.8 | 1.0 | Reference | |
| 9.9-12.2 | 1.9 | 1.3-2.9 | |
| 12.3-15.3 | 2.6 | 1.4-4.7 | |
| Greater than 15.3 | 4.1 | 1.3-12.5 |
Biomarkers . | Adjusted odds ratio* . | 95% confidence interval . | P† . |
|---|---|---|---|
| Lupus anticoagulant, positive | 2.6 | 1.1-6.0 | .025 |
| Anticardiolipin IgM, MPL units | <.001 | ||
| 0.8-8.0 | 1.0 | Reference | |
| 8.1-11.0 | 1.7 | 1.1-2.6 | |
| 11.3-17.0 | 1.9 | 0.9-4.0 | |
| Greater than 17.0 | 3.5 | 1.2-10.1 | |
| Antiphosphatidylethanolamine IgM‡ | .001 | ||
| 0-0.267 | 1.0 | Reference | |
| 0.268-0.450 | 1.3 | 0.9-1.9 | |
| 0.453-0.539 | 1.4 | 0.7-3.0 | |
| Greater than 0.539 | 4.7 | 1.9-12.1 | |
| Anti-annexin V IgG‡ | .005 | ||
| 0.030-0.165 | 1.0 | Reference | |
| 0.166-0.263 | 1.4 | 1.0-2.1 | |
| 0.265-0.366 | 1.3 | 0.6-2.7 | |
| Greater than 0.366 | 3.2 | 1.1-9.1 | |
| Antitissue type plasminogen activator IgG† | <.001 | ||
| 0.0.087 | 1.0 | Reference | |
| 0.088-0.157 | 8.5 | 5.9-12.1 | |
| 0.159-0.259 | 8.1 | 4.7-14.1 | |
| Greater than 0.259 | 19.5 | 7.9-48.0 | |
| Plasma homocysteine, μM | <.001 | ||
| 3.4-9.8 | 1.0 | Reference | |
| 9.9-12.2 | 1.9 | 1.3-2.9 | |
| 12.3-15.3 | 2.6 | 1.4-4.7 | |
| Greater than 15.3 | 4.1 | 1.3-12.5 |