Decreased thymocyte number in tachykinin antagonist-treated mice
Treatment, no. individual mice analyzed . | . | Fractionated thymocytes, × 104 . | . | . | . | |||
|---|---|---|---|---|---|---|---|---|
| . | Total thymocytes, × 105 . | CD4+CD8+ . | CD4+CD8- . | CD4-CD8+ . | CD4-CD8- . | |||
| No treatment, n = 4 | 410 ± 100 | 3300 ± 600 | 460 ± 290 | 140 ± 70 | 200 ± 80 | |||
| DMSO solvent, n = 4 | 370 ± 150 | 2900 ± 1300 | 380 ± 130 | 140 ± 70 | 190 ± 80 | |||
| Antagonist, n = 6* | 9 ± 16 | 5 ± 9 | 53 ± 92 | 27 ± 50 | 9 ± 10 | |||
Treatment, no. individual mice analyzed . | . | Fractionated thymocytes, × 104 . | . | . | . | |||
|---|---|---|---|---|---|---|---|---|
| . | Total thymocytes, × 105 . | CD4+CD8+ . | CD4+CD8- . | CD4-CD8+ . | CD4-CD8- . | |||
| No treatment, n = 4 | 410 ± 100 | 3300 ± 600 | 460 ± 290 | 140 ± 70 | 200 ± 80 | |||
| DMSO solvent, n = 4 | 370 ± 150 | 2900 ± 1300 | 380 ± 130 | 140 ± 70 | 190 ± 80 | |||
| Antagonist, n = 6* | 9 ± 16 | 5 ± 9 | 53 ± 92 | 27 ± 50 | 9 ± 10 | |||
All data are given as the mean ± standard deviation (SD) per lobe.
P < .05 with paired, 2-tailed t tests between solvent and antagonist.