Table 3.

Impact of BAALC expression on clinical outcome




Low BAALC n = 43

High BAALC n = 43

P
Complete remission, n (%)   35 (81)   33 (77)   .79  
Relapse rate, n (%)   10 (29)   17 (52)   .08  
Death in CR, n (%)   2 (6)   3 (9)   .67  
Overall survival     
    Median, y   5.8*  1.7   
    Percent alive at 3 y (95% CI)   60 (45-75)   39 (24-54)   .02  
Event-free survival     
    Median, y   4.9*  0.8   
    Percent event-free at 3 y (95% CI)   55 (40-70)   30 (16-43)   .03  
Disease-free survival     
    Median, y   7.3*  1.4   
    Percent disease-free at 3 y (95% CI)
 
68 (52-84)
 
39 (22-56)
 
.03
 



Low BAALC n = 43

High BAALC n = 43

P
Complete remission, n (%)   35 (81)   33 (77)   .79  
Relapse rate, n (%)   10 (29)   17 (52)   .08  
Death in CR, n (%)   2 (6)   3 (9)   .67  
Overall survival     
    Median, y   5.8*  1.7   
    Percent alive at 3 y (95% CI)   60 (45-75)   39 (24-54)   .02  
Event-free survival     
    Median, y   4.9*  0.8   
    Percent event-free at 3 y (95% CI)   55 (40-70)   30 (16-43)   .03  
Disease-free survival     
    Median, y   7.3*  1.4   
    Percent disease-free at 3 y (95% CI)
 
68 (52-84)
 
39 (22-56)
 
.03
 

CI indicates confidence interval.

*

Nonparametric estimate of the median is not available. Tabled value represents the median, assuming the survival estimate after the last observation follows an exponential curve. The median follow-up for patients alive was 3.3 years (range, 1.6-5.0 years, n = 40).

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