CD3+ T cells infused and cell expansion per dose level
. | Total cells, × 109 . | CD3+, % . | CD4/CD8 ratio . | Fold expansion . |
|---|---|---|---|---|
| Dose level 1: 2.5 × 109 | ||||
| UPN3 | 0.39 | 98.7* | 0.26* | 7.33 |
| UPN5 | 0.20 | 97.7* | 1.97* | 0.42 |
| UPN6 | 1.35 | 97.6 | 7.68 | 2.94 |
| UPN9 | 2.5 | 97.7 | 1.53 | 10.9 |
| Dose level 2: 5 × 109 | ||||
| UPN13 | 5.0 | 93.4 | 1.48 | 9.95 |
| UPN14 | 5.0 | 91.5 | 0.31 | 51.2 |
| UPN15 | 0.52 | 88.2 | 0.83 | 1.04 |
| UPN18 | 1.23 | 87.5 | 1.76 | 2.11 |
| UPN19 | 2.53 | 93.5 | 2.05 | 9.14 |
| UPN20 | 1.52 | 96.7 | 0.26 | 6.62 |
| UPN21 | 0.9 | 95.1 | 4.53 | 1.31 |
| UPN24 | 3.54 | 90.2 | 0.30 | 3.59 |
| UPN25 | 2.91 | 99.1 | 2.81 | 5.87 |
| UPN23 | 1.67 | 92.1 | 1.71 | 4.50 |
| Dose level 3: 10 × 109 | ||||
| UPN26 | 9.46 | 98.5 | 0.87 | 5.32 |
| UPN27 | 10.2 | 96.6 | 0.43 | 21.52 |
. | Total cells, × 109 . | CD3+, % . | CD4/CD8 ratio . | Fold expansion . |
|---|---|---|---|---|
| Dose level 1: 2.5 × 109 | ||||
| UPN3 | 0.39 | 98.7* | 0.26* | 7.33 |
| UPN5 | 0.20 | 97.7* | 1.97* | 0.42 |
| UPN6 | 1.35 | 97.6 | 7.68 | 2.94 |
| UPN9 | 2.5 | 97.7 | 1.53 | 10.9 |
| Dose level 2: 5 × 109 | ||||
| UPN13 | 5.0 | 93.4 | 1.48 | 9.95 |
| UPN14 | 5.0 | 91.5 | 0.31 | 51.2 |
| UPN15 | 0.52 | 88.2 | 0.83 | 1.04 |
| UPN18 | 1.23 | 87.5 | 1.76 | 2.11 |
| UPN19 | 2.53 | 93.5 | 2.05 | 9.14 |
| UPN20 | 1.52 | 96.7 | 0.26 | 6.62 |
| UPN21 | 0.9 | 95.1 | 4.53 | 1.31 |
| UPN24 | 3.54 | 90.2 | 0.30 | 3.59 |
| UPN25 | 2.91 | 99.1 | 2.81 | 5.87 |
| UPN23 | 1.67 | 92.1 | 1.71 | 4.50 |
| Dose level 3: 10 × 109 | ||||
| UPN26 | 9.46 | 98.5 | 0.87 | 5.32 |
| UPN27 | 10.2 | 96.6 | 0.43 | 21.52 |
Day of harvest — 1.