Table 2.

Thirty-five genes (36 probe sets) associated with prognosis of pediatric AML





P

Median expression value
Gene symbol
Gene name
Probe set ID
t test
PP patients
GP patients
VDAC1  Voltage-dependent anion channel 1   40198_at   .0002   365.6   201.3  
ZYX  Zyxin   36958_at   .0005   403.4   905.5  
VAT1  Vesicle amine transport protein 1   40147_at   .0007   342.0   757.1  
   605_at   .0042   239.4   479.5  
NPC2  Niemann-Pick disease type C2   39345_at   .0008   560.6   881.3  
AZU1  Azurocidin 1   33963_at   .0015   -149.8   3509.6  
ECGF1  Endothelial cell growth factor 1   36879_at   .0018   -7.5   372.3  
HOMER-3  Homer-3   38233_at   .0020   104.0   290.3  
PGD  Phosphogluconate dehydrogenase   36963_at   .0022   1041.7   1866.1  
ENSA  Endosulfine α   39011_at   .0025   467.7   393.4  
TKT  Transketolase   38789_at   .0028   892.2   1981.9  
BST1  Bone marrow stromal cell antigen 1   32675_at   .0030   70.5   219.6  
STK17B  Serine/threonine kinase 17b   33390_at   .0033   252.7   946.8  
CDK6  Cyclin-dependent kinase 6   1207_at   .0034   217.8   138.0  
RAB32  Rab32   41523_at   .0035   94.5   236.1  
PTP4A2  Protein tyrosine phosphatase type 4A member 2   1241_at   .0040   582.7   745.4  
APLP2  Amyloid β A4 precursor-like protein 2   33944_at   .0041   602.8   1023.1  
CYLN2  Cytoplasmic linker 2   41396_at   .0041   261.7   139.9  
OGT O-linked N-acetylglucosamine transferase   38614_s_at   .0044   211.7   116.3  
HNRPD  Heterogeneous nuclear ribonucleoprotein D   38016_at   .0059   701.6   546.4  
(W28504)  EST   36338_at   .0060   450.5   251.6  
(D50525)  EST   33683_at   .0061   243.4   192.9  
POLR2H  RNA polymerase 2 polypeptide H   35631_at   .0064   200.2   144.0  
TIAL1  TIA1 cytotoxic granule-associated RNA binding protein-like 1   41763_g_at   .0067   316.2   238.5  
ATP6F  Lysosomal H(+)-transporting ATPase subunit F   36167_at   .0075   844.2   1113.3  
NME1  Protein expressed in nonmetastatic cells 1   1985_s_at   .0076   822.4   455.2  
GRIK5  Ionotropic glutamate receptor kainate 5   34905_at   .0078   209.8   103.8  
CD14  CD14 antigen   36661_s_at   .0078   2.4   583.8  
GABARAP  GABA(A) receptor-associated protein   37298_at   .0080   911.4   1728.7  
NFKBIA  NF-κB inhibitor α   1461_at   .0080   1012.4   1738.7  
GCN5L2  GCN5-like 2   38628_at   .0080   406.8   258.9  
HSPE1  Heat shock protein 1, 10 kDa   39353_at   .0083   540.6   330.4  
LBR  Laminin B receptor   288_s_at   .0088   222.6   430.3  
ECE2  Endothelin converting enzyme 2   35536_at   .0090   248.8   170.7  
BZRP  Benzodiazepine receptor   32806_at   .0093   1690.0   2937.9  
XPO1
 
Exportin 1
 
37729_at
 
.0094
 
733.5
 
443.0
 




P

Median expression value
Gene symbol
Gene name
Probe set ID
t test
PP patients
GP patients
VDAC1  Voltage-dependent anion channel 1   40198_at   .0002   365.6   201.3  
ZYX  Zyxin   36958_at   .0005   403.4   905.5  
VAT1  Vesicle amine transport protein 1   40147_at   .0007   342.0   757.1  
   605_at   .0042   239.4   479.5  
NPC2  Niemann-Pick disease type C2   39345_at   .0008   560.6   881.3  
AZU1  Azurocidin 1   33963_at   .0015   -149.8   3509.6  
ECGF1  Endothelial cell growth factor 1   36879_at   .0018   -7.5   372.3  
HOMER-3  Homer-3   38233_at   .0020   104.0   290.3  
PGD  Phosphogluconate dehydrogenase   36963_at   .0022   1041.7   1866.1  
ENSA  Endosulfine α   39011_at   .0025   467.7   393.4  
TKT  Transketolase   38789_at   .0028   892.2   1981.9  
BST1  Bone marrow stromal cell antigen 1   32675_at   .0030   70.5   219.6  
STK17B  Serine/threonine kinase 17b   33390_at   .0033   252.7   946.8  
CDK6  Cyclin-dependent kinase 6   1207_at   .0034   217.8   138.0  
RAB32  Rab32   41523_at   .0035   94.5   236.1  
PTP4A2  Protein tyrosine phosphatase type 4A member 2   1241_at   .0040   582.7   745.4  
APLP2  Amyloid β A4 precursor-like protein 2   33944_at   .0041   602.8   1023.1  
CYLN2  Cytoplasmic linker 2   41396_at   .0041   261.7   139.9  
OGT O-linked N-acetylglucosamine transferase   38614_s_at   .0044   211.7   116.3  
HNRPD  Heterogeneous nuclear ribonucleoprotein D   38016_at   .0059   701.6   546.4  
(W28504)  EST   36338_at   .0060   450.5   251.6  
(D50525)  EST   33683_at   .0061   243.4   192.9  
POLR2H  RNA polymerase 2 polypeptide H   35631_at   .0064   200.2   144.0  
TIAL1  TIA1 cytotoxic granule-associated RNA binding protein-like 1   41763_g_at   .0067   316.2   238.5  
ATP6F  Lysosomal H(+)-transporting ATPase subunit F   36167_at   .0075   844.2   1113.3  
NME1  Protein expressed in nonmetastatic cells 1   1985_s_at   .0076   822.4   455.2  
GRIK5  Ionotropic glutamate receptor kainate 5   34905_at   .0078   209.8   103.8  
CD14  CD14 antigen   36661_s_at   .0078   2.4   583.8  
GABARAP  GABA(A) receptor-associated protein   37298_at   .0080   911.4   1728.7  
NFKBIA  NF-κB inhibitor α   1461_at   .0080   1012.4   1738.7  
GCN5L2  GCN5-like 2   38628_at   .0080   406.8   258.9  
HSPE1  Heat shock protein 1, 10 kDa   39353_at   .0083   540.6   330.4  
LBR  Laminin B receptor   288_s_at   .0088   222.6   430.3  
ECE2  Endothelin converting enzyme 2   35536_at   .0090   248.8   170.7  
BZRP  Benzodiazepine receptor   32806_at   .0093   1690.0   2937.9  
XPO1
 
Exportin 1
 
37729_at
 
.0094
 
733.5
 
443.0
 

Shown are the 35 genes (36 probe sets) with P < .01 according to the t test and with median expression values greater than 200 in the PP or GP patients.

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