Comparison of leukocytosis and neutrophilia between selectin-perturbed KO mice
. | Fold increase in cell numbers compared with control mice . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
Blood cell types . | β4GalT-1 KO . | Core 2 β6GnT KO . | E/P-selectin KO . | Fuc-TVII KO . | Fuc-TIV/VII KO . | ||||
Leukocytes | 2.2 | 2.4 | 3.9 | 3.2 | 2.9 | ||||
Neutrophils | 2.3 | 4.3 | 16.6 | 7.4 | 18.4 | ||||
Lymphocytes | 2.5 | 1.6 | 1.5 | 2.0 | 1.2 | ||||
Monocytes | 1.6 | 1.4 | 9.8 | 2.9 | 4.2 |
. | Fold increase in cell numbers compared with control mice . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
Blood cell types . | β4GalT-1 KO . | Core 2 β6GnT KO . | E/P-selectin KO . | Fuc-TVII KO . | Fuc-TIV/VII KO . | ||||
Leukocytes | 2.2 | 2.4 | 3.9 | 3.2 | 2.9 | ||||
Neutrophils | 2.3 | 4.3 | 16.6 | 7.4 | 18.4 | ||||
Lymphocytes | 2.5 | 1.6 | 1.5 | 2.0 | 1.2 | ||||
Monocytes | 1.6 | 1.4 | 9.8 | 2.9 | 4.2 |
Data are from core 2 β6GnT-deficient mice,11 E- and P-selectin double-deficient mice,30 Fuc-TVII-deficient mice,13 and Fuc-TIV/VII double-deficient mice.14
KO indicates knockout.