Table 1. Comparison of leukocytosis and... | American Society of Hematology

Table 1.

Comparison of leukocytosis and neutrophilia between selectin-perturbed KO mice

	Fold increase in cell numbers compared with control mice
Blood cell types	β4GalT-1 KO	Core 2 β6GnT KO	E/P-selectin KO	Fuc-TVII KO	Fuc-TIV/VII KO
Leukocytes	2.2	2.4	3.9	3.2	2.9
Neutrophils	2.3	4.3	16.6	7.4	18.4
Lymphocytes	2.5	1.6	1.5	2.0	1.2
Monocytes	1.6	1.4	9.8	2.9	4.2

	Fold increase in cell numbers compared with control mice
Blood cell types	β4GalT-1 KO	Core 2 β6GnT KO	E/P-selectin KO	Fuc-TVII KO	Fuc-TIV/VII KO
Leukocytes	2.2	2.4	3.9	3.2	2.9
Neutrophils	2.3	4.3	16.6	7.4	18.4
Lymphocytes	2.5	1.6	1.5	2.0	1.2
Monocytes	1.6	1.4	9.8	2.9	4.2

Data are from core 2 β6GnT-deficient mice,¹¹ E- and P-selectin double-deficient mice,³⁰ Fuc-TVII-deficient mice,¹³ and Fuc-TIV/VII double-deficient mice.¹⁴

KO indicates knockout.

View Large

This Feature Is Available To Subscribers Only