Correlation between cyclin D1 expression and patient clinical and laboratory characteristics
. | Cyclin D1 . | . | . | |
|---|---|---|---|---|
. | Overexpressed, group A . | Not overexpressed, group B . | P . | |
| No. of patients | 32 | 42 | ||
| Median age, y | 55.0 | 51.5 | .33 | |
| Male-to-female ratio, n | 21:11 | 31:11 | .12 | |
| Durie & Salmon stage, n | ||||
| I | 3 | 11 | ||
| II | 4 | 8 | .27 | |
| III | 25 | 23 | ||
| M component isotype, n | ||||
| IgG | 17 | 26 | .66 | |
| IgA | 8 | 10 | ||
| BJ | 7 | 6 | ||
| L chain, n | ||||
| κ | 20 | 28 | .92 | |
| λ | 12 | 14 | ||
| Median M component concentration | ||||
| IgG, g/L (range) | 39.0 (10.0-111.7) | 42.0 (25.5-84.0) | ||
| IgA, g/L (range) | 38.0 (22.0-42.0) | 36.5 (25.6-78.0) | .35 | |
| BJ, g/24 h (range) | 3.40 (1.90-6.40) | 4.25 (1.90-18.60) | ||
| Median BMPC, % (range) | 50 (10-100) | 40 (10-100) | .20 | |
| Median β2-m level, mg/L (range) | 2.80 (1.20-16.00) | 2.20 (1.10-6.90) | .15 | |
| Median CRP level, mg/L (range) | 3.60 (1-62.5) | 3.10 (1-70.20) | .80 | |
| Median creatinine level, μM (range) | 79.56 (61.88-123.76) | 97.24 (61.88-265.2) | .12 | |
. | Cyclin D1 . | . | . | |
|---|---|---|---|---|
. | Overexpressed, group A . | Not overexpressed, group B . | P . | |
| No. of patients | 32 | 42 | ||
| Median age, y | 55.0 | 51.5 | .33 | |
| Male-to-female ratio, n | 21:11 | 31:11 | .12 | |
| Durie & Salmon stage, n | ||||
| I | 3 | 11 | ||
| II | 4 | 8 | .27 | |
| III | 25 | 23 | ||
| M component isotype, n | ||||
| IgG | 17 | 26 | .66 | |
| IgA | 8 | 10 | ||
| BJ | 7 | 6 | ||
| L chain, n | ||||
| κ | 20 | 28 | .92 | |
| λ | 12 | 14 | ||
| Median M component concentration | ||||
| IgG, g/L (range) | 39.0 (10.0-111.7) | 42.0 (25.5-84.0) | ||
| IgA, g/L (range) | 38.0 (22.0-42.0) | 36.5 (25.6-78.0) | .35 | |
| BJ, g/24 h (range) | 3.40 (1.90-6.40) | 4.25 (1.90-18.60) | ||
| Median BMPC, % (range) | 50 (10-100) | 40 (10-100) | .20 | |
| Median β2-m level, mg/L (range) | 2.80 (1.20-16.00) | 2.20 (1.10-6.90) | .15 | |
| Median CRP level, mg/L (range) | 3.60 (1-62.5) | 3.10 (1-70.20) | .80 | |
| Median creatinine level, μM (range) | 79.56 (61.88-123.76) | 97.24 (61.88-265.2) | .12 | |
Abbreviations are explained in Table 1.