Table 1.

Partner loci of BCL6 translocations determined by LDI-PCR




Case no.
Partner
Chromosomal locus
Group known to transform
Group not known to transform
Involved gene    17 (14)*  8  
    IGH  14q32   2   2  
    CIITA  16p13   4   2  
    RhoH/TTF  4p13   2   0  
    MBNL  3q25   1   1  
    EIF4A2  3q27.3   1   0  
    U50HG  6q15   1   0  
    GRHPR  9p11.2   1   0  
    LRMP  12q12.1   1   0  
    LOC92656 (similar to NAPA)   19q13.33   1   0  
    SIATI  3q26.33   0   2  
    Currently uncharacterized    3   1  
Deletion of BCL6  NA   2   1  
Mutation of BCL6  NA   2   2  
Total
 
NA
 
21
 
11
 



Case no.
Partner
Chromosomal locus
Group known to transform
Group not known to transform
Involved gene    17 (14)*  8  
    IGH  14q32   2   2  
    CIITA  16p13   4   2  
    RhoH/TTF  4p13   2   0  
    MBNL  3q25   1   1  
    EIF4A2  3q27.3   1   0  
    U50HG  6q15   1   0  
    GRHPR  9p11.2   1   0  
    LRMP  12q12.1   1   0  
    LOC92656 (similar to NAPA)   19q13.33   1   0  
    SIATI  3q26.33   0   2  
    Currently uncharacterized    3   1  
Deletion of BCL6  NA   2   1  
Mutation of BCL6  NA   2   2  
Total
 
NA
 
21
 
11
 

NA indicates not applicable.

*

Three cases had two independent BCL6 partners (see Table 3).

Chromosomal loci for currently uncharacterized partners are described in the text.

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