Characteristics of study population (N = 28)
Characteristic . | No. . |
---|---|
Male | 20 |
Female | 8 |
Hematologic malignancy | |
Acute lymphoblastic leukemia | 5 |
Chronic myeloid leukemia | 14 |
Acute myelogenous leukemia | 6 |
Myeloma | 3 |
Donor | |
Sibling | 19 |
Matched unrelated | 9 |
Donor lymphocyte infusion | 11 |
cGVHD disease type | |
Progressive | 9 |
De novo | 14 |
Relapsed | 5 |
Predictive factors | |
More than 50% cutaneous involvement | 20 |
Progressive cGVHD | 9 |
Platelet count less than 100 × 109/L | 1 |
No predictive factors | 4 |
1 of 3 predictive factors | 17 |
2 of 3 predictive factors | 7 |
Systemic therapy | |
Prednisolone/methylprednisolone | 26 |
Cyclosporin | 24 |
Mycophenolate mofetil | 7 |
Thalidomide | 5 |
PUVA | 5 |
Azathioprine | 4 |
Tacrolimus (FK 506) | 2 |
Methotrexate | 1 |
Cyclophosphamide | 1 |
Median delay before starting ECP, mo (range) | |
From diagnosis | 45 (15-193) |
From allograft | 34 (10-167) |
From onset of cGVHD | 23 (2-164) |
Characteristic . | No. . |
---|---|
Male | 20 |
Female | 8 |
Hematologic malignancy | |
Acute lymphoblastic leukemia | 5 |
Chronic myeloid leukemia | 14 |
Acute myelogenous leukemia | 6 |
Myeloma | 3 |
Donor | |
Sibling | 19 |
Matched unrelated | 9 |
Donor lymphocyte infusion | 11 |
cGVHD disease type | |
Progressive | 9 |
De novo | 14 |
Relapsed | 5 |
Predictive factors | |
More than 50% cutaneous involvement | 20 |
Progressive cGVHD | 9 |
Platelet count less than 100 × 109/L | 1 |
No predictive factors | 4 |
1 of 3 predictive factors | 17 |
2 of 3 predictive factors | 7 |
Systemic therapy | |
Prednisolone/methylprednisolone | 26 |
Cyclosporin | 24 |
Mycophenolate mofetil | 7 |
Thalidomide | 5 |
PUVA | 5 |
Azathioprine | 4 |
Tacrolimus (FK 506) | 2 |
Methotrexate | 1 |
Cyclophosphamide | 1 |
Median delay before starting ECP, mo (range) | |
From diagnosis | 45 (15-193) |
From allograft | 34 (10-167) |
From onset of cGVHD | 23 (2-164) |