Table 1. Concentration of imatinib in... | American Society of Hematology

Table 1.

Concentration of imatinib in MDR⁺ and MDR^- cells at various imatinib incubation levels

Incubation medium, ng/mL	Intracellular, ng/μg prot	Extracellular, ng/μg prot	Intra/extracellular ratio
MDR1⁺
500	0.07 ± 0.006	2.86 ± 0.481	0.023
1500	0.10 ± 0.002	5.70 ± 0.687	0.017
3000	0.26 ± 0.031	12.70 ± 0.322	0.020
MDR1^-
500	0.24 ± 0.004	3.04 ± 0.143	0.079
1500	1.15 ± 0.190	5.92 ± 0.326	0.195
3000	6.14 ± 0.432	11.17 ± 0.384	0.550

Incubation medium, ng/mL	Intracellular, ng/μg prot	Extracellular, ng/μg prot	Intra/extracellular ratio
MDR1⁺
500	0.07 ± 0.006	2.86 ± 0.481	0.023
1500	0.10 ± 0.002	5.70 ± 0.687	0.017
3000	0.26 ± 0.031	12.70 ± 0.322	0.020
MDR1^-
500	0.24 ± 0.004	3.04 ± 0.143	0.079
1500	1.15 ± 0.190	5.92 ± 0.326	0.195
3000	6.14 ± 0.432	11.17 ± 0.384	0.550