Table 4.

Other hematologic malignancies associated with chromsomal translocations in which large deletions have been demonstrated by FISH


Translocation

Fusion partners

Associated hematologic malignancy

Incidence (%)

Reference no.
t(9;22)  BCR-ABL  ALL   2/80 (2)  51, 74  
inv(16)  CBFβ-MYH11  AML   2/20 (10)  51  
t(8;21)  AML1-ETO  AML   6/79 (8)  51,108  
11q23
 
MLL + multiple partners
 
AL
 
9/58 (16)
 
51,107 
 

Translocation

Fusion partners

Associated hematologic malignancy

Incidence (%)

Reference no.
t(9;22)  BCR-ABL  ALL   2/80 (2)  51, 74  
inv(16)  CBFβ-MYH11  AML   2/20 (10)  51  
t(8;21)  AML1-ETO  AML   6/79 (8)  51,108  
11q23
 
MLL + multiple partners
 
AL
 
9/58 (16)
 
51,107 
 

The published incidence of deletions from FISH studies is shown. ALL indicates acute lymphoblastic leukemia; AML, acute myeloid leukemia; and AL, acute leukemia.

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