Deletion status is a more powerful prognostic indicator than either the Sokal or Hasford clinical scores
. | High-risk . | . | Non—high-risk . | . | . | ||
|---|---|---|---|---|---|---|---|
| Prognostic factor . | Patients, % . | Median survival (95% CI) . | Patients, % . | Median survival (95% CI) . | Survival difference, P . | ||
| Deletion status | 15 | 37 (25-49) | 85 | 81 (51-110) | .0001 | ||
| Sokal | 37 | 56 (40-72) | 63 | 72 (51-93) | .057 | ||
| Hasford | 22 | 55 (34-76) | 78 | 76 (49-103) | .034 | ||
. | High-risk . | . | Non—high-risk . | . | . | ||
|---|---|---|---|---|---|---|---|
| Prognostic factor . | Patients, % . | Median survival (95% CI) . | Patients, % . | Median survival (95% CI) . | Survival difference, P . | ||
| Deletion status | 15 | 37 (25-49) | 85 | 81 (51-110) | .0001 | ||
| Sokal | 37 | 56 (40-72) | 63 | 72 (51-93) | .057 | ||
| Hasford | 22 | 55 (34-76) | 78 | 76 (49-103) | .034 | ||
Non—high-risk refers to patients lacking a derivative chromosome 9 deletion or, in the Sokal and Hasford systems, the combined low- and intermediate-risk groups. High-risk refers to patients with a deletion or to Sokal and Hasford high-risk groups. Comparison of survival was made by log-rank analysis with the P values shown. Data are reprinted from Huntly et al50 with permission.