Initial characteristics of transplantation study groups
. | ISD . | MFD . | MUD . | P . |
|---|---|---|---|---|
| N, total | 138 | 86 | 101 | |
| Patient age | ||||
| Median, y (range) | 40.5 (16-59) | 35.5 (16-57) | 40.0 (16-57) | .008* |
| Older than 37 y (%) | 84 (61) | 32 (37) | 58 (57) | .002† |
| Patient sex, n, M:F (ratio) | 79:59 (1.3:1) | 49:37 (1.3:1) | 58:43 (1.3:1) | NS† |
| Diagnosis (%) | NS† | |||
| CML | 107 (77) | 56 (65) | 76 (75) | |
| AML | 27 (20) | 25 (29) | 17 (17) | |
| ALL | 4 (3) | 5 (6) | 8 (8) | |
| Disease stage | ||||
| Early vs advanced (%) | 110 vs 28 (80 vs 20) | 48 vs 38 (56 vs 44) | 66 vs 35 (65 vs 35) | .001† |
| Interval: diagnosis → TX, d, median (range) | ||||
| CML | 490 (38-5.162) | 573 (111-4.057) | 678 (102-5.182) | <.0001‡ |
| AML/ALL | 190 (72-1.293) | 280 (120-1.589) | 601 (104-2.003) | .001‡ |
| Stem cell source | ||||
| BM vs PB (%) | 80 vs 58 (58 vs 42) | 40 vs 46 (46 vs 54) | 76 vs 25 (75 vs 25) | <.0001† |
| Donor age, y | ||||
| Median (range) | 41 (12-54) | 43 (9-71) | 36 (20-59) | .006* |
| Older than 38 y (%) | 78/138 (56) | 50/86 (58) | 35/101 (35) | .001† |
| Donor sex, n, M:F (ratio) | 63:75 (0.8:1) | 38:48 (0.8:1) | 65:36 (1.8:1) | .006† |
| Sex mismatch, | ||||
| yes, donor F, patient M (%) | 43/138 (31) | 27/86 (31) | 13/101 (13) | .001† |
. | ISD . | MFD . | MUD . | P . |
|---|---|---|---|---|
| N, total | 138 | 86 | 101 | |
| Patient age | ||||
| Median, y (range) | 40.5 (16-59) | 35.5 (16-57) | 40.0 (16-57) | .008* |
| Older than 37 y (%) | 84 (61) | 32 (37) | 58 (57) | .002† |
| Patient sex, n, M:F (ratio) | 79:59 (1.3:1) | 49:37 (1.3:1) | 58:43 (1.3:1) | NS† |
| Diagnosis (%) | NS† | |||
| CML | 107 (77) | 56 (65) | 76 (75) | |
| AML | 27 (20) | 25 (29) | 17 (17) | |
| ALL | 4 (3) | 5 (6) | 8 (8) | |
| Disease stage | ||||
| Early vs advanced (%) | 110 vs 28 (80 vs 20) | 48 vs 38 (56 vs 44) | 66 vs 35 (65 vs 35) | .001† |
| Interval: diagnosis → TX, d, median (range) | ||||
| CML | 490 (38-5.162) | 573 (111-4.057) | 678 (102-5.182) | <.0001‡ |
| AML/ALL | 190 (72-1.293) | 280 (120-1.589) | 601 (104-2.003) | .001‡ |
| Stem cell source | ||||
| BM vs PB (%) | 80 vs 58 (58 vs 42) | 40 vs 46 (46 vs 54) | 76 vs 25 (75 vs 25) | <.0001† |
| Donor age, y | ||||
| Median (range) | 41 (12-54) | 43 (9-71) | 36 (20-59) | .006* |
| Older than 38 y (%) | 78/138 (56) | 50/86 (58) | 35/101 (35) | .001† |
| Donor sex, n, M:F (ratio) | 63:75 (0.8:1) | 38:48 (0.8:1) | 65:36 (1.8:1) | .006† |
| Sex mismatch, | ||||
| yes, donor F, patient M (%) | 43/138 (31) | 27/86 (31) | 13/101 (13) | .001† |