Percentage of cases with complete chimerism after infusion of CD34+ and CD3+ cells
Source of sample analyzed . | Days after transplantation . | . | . | . | . | . | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| . | 21-28 . | 56 . | 100 . | 180 . | 270 . | 365 . | |||||
| Bone marrow | 73 | 81 | 83 | 88 | 86 | 88 | |||||
| Unseparated peripheral blood | 88 | 82 | 91 | 100 | 100 | 100 | |||||
| T lymphocytes | 57* | 58 | 73 | 88 | 100 | 100 | |||||
| Granulocytes | 92 | 88 | 92 | 94 | 100 | 100 | |||||
Source of sample analyzed . | Days after transplantation . | . | . | . | . | . | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| . | 21-28 . | 56 . | 100 . | 180 . | 270 . | 365 . | |||||
| Bone marrow | 73 | 81 | 83 | 88 | 86 | 88 | |||||
| Unseparated peripheral blood | 88 | 82 | 91 | 100 | 100 | 100 | |||||
| T lymphocytes | 57* | 58 | 73 | 88 | 100 | 100 | |||||
| Granulocytes | 92 | 88 | 92 | 94 | 100 | 100 | |||||
100% of patients receiving more than p75 vs 44% of patients receiving p75 or fewer CD34+ cells reached complete chimerism (P = .046); in all other instances, cell dose had no significant influence on the kinetics of complete chimerism