Change of cell number of lymphocyte subpopulations after pamidronate/IL-2 infusion of patients from cohort B
. | . | . | . | Increase γδ T cells, % mean (range) . | . | |
|---|---|---|---|---|---|---|
| Dose level, IL-2 IU/m2 . | Patients, n . | Increase αβ T cells, % mean (range) . | Increase NK cells, % mean (range) . | Vδ1 (range) . | Vγ9δ2 (range) . | |
| 0.25 × 106 | 3 | 47 (−3-82) | 44 (42-152) | 64 (0-114) | 0 (0) | |
| 0.5 × 106 | 3 | 19 (11-23) | 122 (19-136) | 0 (−3-0) | 128 (24-257) | |
| 1 × 106 | 4 | 35 (7-70) | 30 (0-98) | 0 (0-36) | 89 (−15-210) | |
| 2 × 106 | 3 | 12 (−5-14) | 37 (26-71) | 0 (0-8) | 57 (21-95) | |
. | . | . | . | Increase γδ T cells, % mean (range) . | . | |
|---|---|---|---|---|---|---|
| Dose level, IL-2 IU/m2 . | Patients, n . | Increase αβ T cells, % mean (range) . | Increase NK cells, % mean (range) . | Vδ1 (range) . | Vγ9δ2 (range) . | |
| 0.25 × 106 | 3 | 47 (−3-82) | 44 (42-152) | 64 (0-114) | 0 (0) | |
| 0.5 × 106 | 3 | 19 (11-23) | 122 (19-136) | 0 (−3-0) | 128 (24-257) | |
| 1 × 106 | 4 | 35 (7-70) | 30 (0-98) | 0 (0-36) | 89 (−15-210) | |
| 2 × 106 | 3 | 12 (−5-14) | 37 (26-71) | 0 (0-8) | 57 (21-95) | |
Results represent means of increase in absolute cell numbers on day 7.