Side effects with high-dose imatinib (n = 36)
. | No. (%) with toxicity . | . | |
|---|---|---|---|
| Toxicity . | Any . | Grade 3 or higher . | |
| Fluid retention | 18 (50) | 0 | |
| Bone pain | 15 (42) | 1 (3) | |
| Skin rash | 13 (36) | 3 (8) | |
| Fatigue | 8 (22) | 1 (3) | |
| Nausea/vomiting | 7 (19) | 0 | |
| Diarrhea | 7 (19) | 0 | |
| Abnormal liver function tests | 7 (19) | 1 (3) | |
| Numbness | 1 (3) | 0 | |
| Depression | 1 (3) | 0 | |
| Anemia | 29 (81) | 3 (8) | |
| Neutropenia | 28 (78) | 11 (31) | |
| Thrombocytopenia | 14 (39) | 8 (22) | |
. | No. (%) with toxicity . | . | |
|---|---|---|---|
| Toxicity . | Any . | Grade 3 or higher . | |
| Fluid retention | 18 (50) | 0 | |
| Bone pain | 15 (42) | 1 (3) | |
| Skin rash | 13 (36) | 3 (8) | |
| Fatigue | 8 (22) | 1 (3) | |
| Nausea/vomiting | 7 (19) | 0 | |
| Diarrhea | 7 (19) | 0 | |
| Abnormal liver function tests | 7 (19) | 1 (3) | |
| Numbness | 1 (3) | 0 | |
| Depression | 1 (3) | 0 | |
| Anemia | 29 (81) | 3 (8) | |
| Neutropenia | 28 (78) | 11 (31) | |
| Thrombocytopenia | 14 (39) | 8 (22) | |