Table 5.

Histological features of 114 patients with diffuse large B-cell lymphoma according to differentiation profile

GC-CD10+
(n = 24), %
GC-CD10
(n = 30), %
pGC
(n = 60), %
Immunoblastic and polymorphic morphology (more than 50% immunoblasts)5-150 55-152 24 39  
Ki-67, 25% or less 295-152 2  
bcl-2/JH rearrangement5-151(+) 415-152 0  
Bcl-2 expression (+) 67 50 62  
p53 (+) 37 20 27  
p27 (+) 50 23 45 
GC-CD10+
(n = 24), %
GC-CD10
(n = 30), %
pGC
(n = 60), %
Immunoblastic and polymorphic morphology (more than 50% immunoblasts)5-150 55-152 24 39  
Ki-67, 25% or less 295-152 2  
bcl-2/JH rearrangement5-151(+) 415-152 0  
Bcl-2 expression (+) 67 50 62  
p53 (+) 37 20 27  
p27 (+) 50 23 45 
F5-150

n = 87 patients with centroblastic, polymorphic, or immunoblastic morphology (patients with morphology not further classifiable were excluded).

F5-151

n = 57 patients in whom PCR for bcl-2/JH was performed.

F5-152

P < .05 vs the other groups.

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