ICSBP−/− mice are not deficient in common myeloid and lymphoid bone marrow progenitors
| . | CMP (P) . | CLP (P) . | HSC (P) . |
|---|---|---|---|
| WT | 15.1 ± 1.21 | 3.64 ± 0.36 | 12.7 ± 3.1 |
| ICSBP−/− | 13.3 ± 2.84 (.544) | 2.73 ± 0.69 (.121) | 19.1 ± 2.8 (.081) |
| . | CMP (P) . | CLP (P) . | HSC (P) . |
|---|---|---|---|
| WT | 15.1 ± 1.21 | 3.64 ± 0.36 | 12.7 ± 3.1 |
| ICSBP−/− | 13.3 ± 2.84 (.544) | 2.73 ± 0.69 (.121) | 19.1 ± 2.8 (.081) |
Numbers are cells/mouse (×104; n = 3/group).P values are significance of difference between ICSBP−/− and wild-type levels. CMP indicates common myeloid progenitor (CD117+CD34+CD16/3210Sca-1−); CLP, common lymphoid progenitor (CD117+Sca-1+CD127+Lin−); HSC, hemopoietic stem cell (CD117+Sca-1+CD90+CD127−Lin−); WT, wild-type.