Hematologic values for control and Hfe mutant mice treated with PHZ or by phlebotomy
| . | +/+ . | −/− . | Y/Y . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Control (n = 20) . | PHZ (n = 8) . | Phlebotomy (n = 9) . | Control (n = 22) . | PHZ (n = 7) . | Phlebotomy (n = 9) . | Control (n = 18) . | PHZ (n = 11) . | Phlebotomy (n = 5) . | |
| % Reticulocytes | 1.0 ± 0.37 | 15.0 ± 2.6 | 8.9 ± 1.3 | 1.0 ± 0.1 | 11.0 ± 0.6 | 9.8 ± 0.6 | 1.7 ± 0.3 | 13.0 ± 0.6 | 7.0 ± 0.9 |
| % Hematocrit | 48.0 ± 0.8 | 31.5 ± 2.5 | 36.2 ± 2.0 | 48.7 ± 0.8 | 35.2 ± 2.0 | 43.3 ± 1.9 | 46.2 ± 0.8 | 36.0 ± 1.4 | 40.4 ± 2.5 |
| Hemoglobin (g/dL) | 16.5 ± 0.3 | —4-150 | 13.6 ± 0.9 | 16.5 ± 0.3 | —4-150 | 14.6 ± 0.8 | 15.8 ± 0.2 | —4-150 | 13.9 ± 1.3 |
| MCV (fL) | 50.5 ± 0.4 | 56.5 ± 1.0 | 52.3 ± 0.5 | 50.7 ± 0.2 | 58.4 ± 1.0 | 51.4 ± 0.4 | 54.0 ± 0.5 | 56.5 ± 1.0 | 53.2 ± 0.4 |
| . | +/+ . | −/− . | Y/Y . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Control (n = 20) . | PHZ (n = 8) . | Phlebotomy (n = 9) . | Control (n = 22) . | PHZ (n = 7) . | Phlebotomy (n = 9) . | Control (n = 18) . | PHZ (n = 11) . | Phlebotomy (n = 5) . | |
| % Reticulocytes | 1.0 ± 0.37 | 15.0 ± 2.6 | 8.9 ± 1.3 | 1.0 ± 0.1 | 11.0 ± 0.6 | 9.8 ± 0.6 | 1.7 ± 0.3 | 13.0 ± 0.6 | 7.0 ± 0.9 |
| % Hematocrit | 48.0 ± 0.8 | 31.5 ± 2.5 | 36.2 ± 2.0 | 48.7 ± 0.8 | 35.2 ± 2.0 | 43.3 ± 1.9 | 46.2 ± 0.8 | 36.0 ± 1.4 | 40.4 ± 2.5 |
| Hemoglobin (g/dL) | 16.5 ± 0.3 | —4-150 | 13.6 ± 0.9 | 16.5 ± 0.3 | —4-150 | 14.6 ± 0.8 | 15.8 ± 0.2 | —4-150 | 13.9 ± 1.3 |
| MCV (fL) | 50.5 ± 0.4 | 56.5 ± 1.0 | 52.3 ± 0.5 | 50.7 ± 0.2 | 58.4 ± 1.0 | 51.4 ± 0.4 | 54.0 ± 0.5 | 56.5 ± 1.0 | 53.2 ± 0.4 |
Mouse strains are explained in Table 1. Error presented as SEM. Hfe genotypes as in Table 1.
Value outside the linear region of the detector's calibration curve.