Hematologic values and liver iron concentration in control and Hfe mutant mice
| . | +/+ . | −/− . | Y/Y . | |||
|---|---|---|---|---|---|---|
| Control (n = 20) . | Fe-deficient (n = 11) . | Control (n = 22) . | Fe-deficient (n = 12) . | Control (n = 18) . | Fe-deficient (n = 14) . | |
| % Hematocrit | 48.1 ± 0.8 | 48.0 ± 0.7 | 48.7 ± 0.8 | 48.2 ± 1.0 | 46.2 ± 0.8 | 44.9 ± 0.6 |
| Hemoglobin (g/dL) | 16.5 ± 0.3 | 15.4 ± 0.3 | 16.5 ± 0.3 | 14.3 ± 1.4 | 15.8 ± 0.2 | 14.9 ± 0.2 |
| MCV (fL) | 50.5 ± 0.4 | 48.2 ± 0.6 | 50.7 ± 0.2 | 47.6 ± 0.7 | 54.0 ± 0.5 | 49.7 ± 0.3 |
| Liver Fe (μg/g wet weight) | 205.1 ± 10 | 46.4 ± 6.2 | 805.8 ± 60.0 | 48 ± 5.8 | 662.8 ± 53.0 | 80.7 ± 24.7 |
| . | +/+ . | −/− . | Y/Y . | |||
|---|---|---|---|---|---|---|
| Control (n = 20) . | Fe-deficient (n = 11) . | Control (n = 22) . | Fe-deficient (n = 12) . | Control (n = 18) . | Fe-deficient (n = 14) . | |
| % Hematocrit | 48.1 ± 0.8 | 48.0 ± 0.7 | 48.7 ± 0.8 | 48.2 ± 1.0 | 46.2 ± 0.8 | 44.9 ± 0.6 |
| Hemoglobin (g/dL) | 16.5 ± 0.3 | 15.4 ± 0.3 | 16.5 ± 0.3 | 14.3 ± 1.4 | 15.8 ± 0.2 | 14.9 ± 0.2 |
| MCV (fL) | 50.5 ± 0.4 | 48.2 ± 0.6 | 50.7 ± 0.2 | 47.6 ± 0.7 | 54.0 ± 0.5 | 49.7 ± 0.3 |
| Liver Fe (μg/g wet weight) | 205.1 ± 10 | 46.4 ± 6.2 | 805.8 ± 60.0 | 48 ± 5.8 | 662.8 ± 53.0 | 80.7 ± 24.7 |
Mouse strains are explained in Table 1. Error presented as SEM. Hfe genotypes as in Table 1.