Transferrin saturation and liver iron content in control and Hfe mutant mouse strains at 8 weeks of age
| Strain . | % Tf saturation . | Liver iron (μg/g wet weight) . |
|---|---|---|
| +/+ (n = 19) | 51 ± 3 | 223 ± 11 |
| −/− (n = 14) | 83 ± 3* | 936 ± 57* |
| Y/Y (n = 19) | 78 ± 4* | 735 ± 56* |
| Strain . | % Tf saturation . | Liver iron (μg/g wet weight) . |
|---|---|---|
| +/+ (n = 19) | 51 ± 3 | 223 ± 11 |
| −/− (n = 14) | 83 ± 3* | 936 ± 57* |
| Y/Y (n = 19) | 78 ± 4* | 735 ± 56* |
+/+ indicates wild type; −/−, Hfe knockout; Y/Y,Hfe knockin for the C282Y mutation. Error presented as SEM.
Values compared with those for wild type, P< .001.