Relation of bone marrow CD8+ cell IFN-γ to response to immunosuppressive therapy
| . | Positive IFN-γ . | Negative IFN-γ . |
|---|---|---|
| Response to therapy | 20 | 0 |
| Treatment failure | 0 | 10 |
| . | Positive IFN-γ . | Negative IFN-γ . |
|---|---|---|
| Response to therapy | 20 | 0 |
| Treatment failure | 0 | 10 |
Samples of PB and BM were obtained from 26 patients with severe AA before and after immunosuppressive treatment and were analyzed according to response to therapy. Fisher exact test showed a significant difference between responders and nonresponders;P < .00002.