Modulation of Th cell (Th1/Th2) subpopulations by ECP
| Patient . | Baseline to last cycle of ECP treatment (pre-ECP vs post-ECP-fold difference) . | ||||
|---|---|---|---|---|---|
| CD4 . | CD8 . | IFN-γ . | IL-4 . | IL-10 . | |
| 1 | + 1.4 | − 0.7 | − 2.5 | + 1.7 | + 1.3 |
| 2 | + 1.4 | − 1.3 | − 2.7 | + 1.3 | + 3 |
| 3 | + 1.2 | − 0.9 | − 4 | + 4.2 | + 2.5 |
| 4 | + 1.1 | − 0.6 | − 1.1 | + 3.5 | + 4 |
| 5 | + 3 | − 4 | − 2.8 | + 4.6 | + 2 |
| 6 | + 1.6 | − 1.3 | − 1.3 | + 3.5 | + 3.5 |
| 7 | + 1.2 | − 1.3 | − 2.2 | + 3.2 | + 2.4 |
| 8 | + 2.2 | − 3.5 | − 3 | + 3.5 | + 3 |
| 9 | + 2.1 | − 2.5 | − 1.5 | + 2.4 | + 1.4 |
| 10 | + 1.2 | − 3.5 | − 0.6 | + 0.7 | + 0.3 |
| Patient . | Baseline to last cycle of ECP treatment (pre-ECP vs post-ECP-fold difference) . | ||||
|---|---|---|---|---|---|
| CD4 . | CD8 . | IFN-γ . | IL-4 . | IL-10 . | |
| 1 | + 1.4 | − 0.7 | − 2.5 | + 1.7 | + 1.3 |
| 2 | + 1.4 | − 1.3 | − 2.7 | + 1.3 | + 3 |
| 3 | + 1.2 | − 0.9 | − 4 | + 4.2 | + 2.5 |
| 4 | + 1.1 | − 0.6 | − 1.1 | + 3.5 | + 4 |
| 5 | + 3 | − 4 | − 2.8 | + 4.6 | + 2 |
| 6 | + 1.6 | − 1.3 | − 1.3 | + 3.5 | + 3.5 |
| 7 | + 1.2 | − 1.3 | − 2.2 | + 3.2 | + 2.4 |
| 8 | + 2.2 | − 3.5 | − 3 | + 3.5 | + 3 |
| 9 | + 2.1 | − 2.5 | − 1.5 | + 2.4 | + 1.4 |
| 10 | + 1.2 | − 3.5 | − 0.6 | + 0.7 | + 0.3 |
Th1 and Th2 cells were detected by cytokine secretion. Captured cytokines were analyzed by flow cytometry, and results are shown as -fold difference between baseline and last cycle of ECP (increased [+] or decreased [−]). P < .005.