Hematologic response according to duration and previous treatment
| Hematologic response . | All responses (total n = 229) . | Patients with a sustained response (≥ 4 wk) . | ||
|---|---|---|---|---|
| Total (n = 229) . | Previously untreated (n = 148) . | Previously treated (n = 81) . | ||
| Overall* | 119 (52.0) | 70 (30.6) | 53 (35.8) | 17 (21.0) |
| 95% CI (%) | 45.3-58.6 | 24.7-37.0 | 28.1-44.1 | 12.7-31.5 |
| Complete | 35 (15.3) | 18 (7.9) | 13 (8.8) | 5 (6.2) |
| Marrow response | 20 (8.7) | 10 (4.4) | 8 (5.4) | 2 (2.5) |
| Return to chronic phase | 64 (27.9) | 42 (18.3) | 32 (21.6) | 10 (12.3) |
| No response | 108 (47.2) | 152 (66.4) | 92 (62.2) | 60 (74.0) |
| Not evaluable | 2 (0.9) | 7 (3.0) | 3 (2.0) | 4 (4.9) |
| Hematologic response . | All responses (total n = 229) . | Patients with a sustained response (≥ 4 wk) . | ||
|---|---|---|---|---|
| Total (n = 229) . | Previously untreated (n = 148) . | Previously treated (n = 81) . | ||
| Overall* | 119 (52.0) | 70 (30.6) | 53 (35.8) | 17 (21.0) |
| 95% CI (%) | 45.3-58.6 | 24.7-37.0 | 28.1-44.1 | 12.7-31.5 |
| Complete | 35 (15.3) | 18 (7.9) | 13 (8.8) | 5 (6.2) |
| Marrow response | 20 (8.7) | 10 (4.4) | 8 (5.4) | 2 (2.5) |
| Return to chronic phase | 64 (27.9) | 42 (18.3) | 32 (21.6) | 10 (12.3) |
| No response | 108 (47.2) | 152 (66.4) | 92 (62.2) | 60 (74.0) |
| Not evaluable | 2 (0.9) | 7 (3.0) | 3 (2.0) | 4 (4.9) |
Values are numbers (%) of patients unless otherwise indicated. CI indicates confidence interval.
Overall hematologic response was a complete hematologic response, a marrow response, or a return to chronic phase.