Table 1.

Low-density lipoprotein from 62 healthy subjects and a heme oxygenase-1–deficient child compared for oxidative resistance, conjugated dienes, thiobarbituric acid—reactive substances, total lipid hydroperoxide, and α-tocopherol content

ParameterLDL from healthy subjects (n = 62)LDL from HO-1–deficient child
MeanSDMinMaxMeanSD
ΔT at Vmax, s 3040.6 515.2 2220 4740 120 57 
Conj dienes, OD at 234 nm 0.1794 0.0156 0.1471 0.2203 0.436 0.055 
TBARSs, nmol/mg LDL 0.316 0.094 0.128 0.577 1.75 0.31  
Total LOOHs, nmol/mg LDL 4.689 1.417 2.170 8.140 32.6 2.53 
α-tocopherol, mol/mol ApoB-100 7.91 1.85 4.32 14.56 0.20 0.11 
ParameterLDL from healthy subjects (n = 62)LDL from HO-1–deficient child
MeanSDMinMaxMeanSD
ΔT at Vmax, s 3040.6 515.2 2220 4740 120 57 
Conj dienes, OD at 234 nm 0.1794 0.0156 0.1471 0.2203 0.436 0.055 
TBARSs, nmol/mg LDL 0.316 0.094 0.128 0.577 1.75 0.31  
Total LOOHs, nmol/mg LDL 4.689 1.417 2.170 8.140 32.6 2.53 
α-tocopherol, mol/mol ApoB-100 7.91 1.85 4.32 14.56 0.20 0.11 

Conj indicates conjugated; OD, optical density.

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