Allogeneic transplant course and current status
| Patient/sex . | Donor . | Interval auto-allo, d . | ANC* . | Platelets* . | Acute GVHD . | Chronic GVHD . | Current status . |
|---|---|---|---|---|---|---|---|
| 1. M | MUD | 102 | 15 | 14 | None | None | CCR d 720+ |
| 2. M | Rel-id | 60 | 17 | 24 | I° (S) | Limited | CCR d 713+ |
| 3. M | Rel-mm | 103 | 15 | 20 | NE | NE | Died of sepsis d 22 after allograft |
| 4. M | Rel-id | 84 | 16 | 16 | None | None | CCR d 706+ |
| 5. M | Rel-mm | 77 | 16 | 33 | III° (S, G) | Extensive | PD, alive d 610+ |
| 6. M | Rel-id | 94 | 20 | 23 | I° (G) | None | PD, dead d 447 |
| 7. F | Rel-id | 119 | 17 | 43 | None | None | PR†d 591+ |
| 8. M | Rel-id | 135 | 18 | 26 | I° (S) | None | CCR d 566+ |
| 9. M | MUD | 169 | 17 | 33 | II° (S) | Limited | PR d 514+ |
| 10. F | MUD | 210 | 13 | 24 | II° (S) | None | PR‡ d 550+ |
| 11. F | MUD | 146 | 14 | 22 | III° (L, G) | Limited | CCR d 444+ |
| 12. M | MUD | 119 | 22 | 24 | I° (G) | Limited | CCR d 386+ |
| 13. M | MUD-mm | 150 | 15 | 12 | II° (S) | Limited | CCR d 497+ |
| 14. M | MUD | 135 | 13 | 22 | None | None | Died in CR of sudden cardiac arrest d 119 after allograft |
| 15. M | Rel-id | 150 | 11 | NE | NE | NE | Died of MOF d 48 after allograft |
| 16. F | Rel-id | 147 | 17 | 23 | None | None | CCR d 332+ |
| 17. F | MUD | 114 | 16 | 15 | II° (S) | None | MR‡ d 279+ |
| Patient/sex . | Donor . | Interval auto-allo, d . | ANC* . | Platelets* . | Acute GVHD . | Chronic GVHD . | Current status . |
|---|---|---|---|---|---|---|---|
| 1. M | MUD | 102 | 15 | 14 | None | None | CCR d 720+ |
| 2. M | Rel-id | 60 | 17 | 24 | I° (S) | Limited | CCR d 713+ |
| 3. M | Rel-mm | 103 | 15 | 20 | NE | NE | Died of sepsis d 22 after allograft |
| 4. M | Rel-id | 84 | 16 | 16 | None | None | CCR d 706+ |
| 5. M | Rel-mm | 77 | 16 | 33 | III° (S, G) | Extensive | PD, alive d 610+ |
| 6. M | Rel-id | 94 | 20 | 23 | I° (G) | None | PD, dead d 447 |
| 7. F | Rel-id | 119 | 17 | 43 | None | None | PR†d 591+ |
| 8. M | Rel-id | 135 | 18 | 26 | I° (S) | None | CCR d 566+ |
| 9. M | MUD | 169 | 17 | 33 | II° (S) | Limited | PR d 514+ |
| 10. F | MUD | 210 | 13 | 24 | II° (S) | None | PR‡ d 550+ |
| 11. F | MUD | 146 | 14 | 22 | III° (L, G) | Limited | CCR d 444+ |
| 12. M | MUD | 119 | 22 | 24 | I° (G) | Limited | CCR d 386+ |
| 13. M | MUD-mm | 150 | 15 | 12 | II° (S) | Limited | CCR d 497+ |
| 14. M | MUD | 135 | 13 | 22 | None | None | Died in CR of sudden cardiac arrest d 119 after allograft |
| 15. M | Rel-id | 150 | 11 | NE | NE | NE | Died of MOF d 48 after allograft |
| 16. F | Rel-id | 147 | 17 | 23 | None | None | CCR d 332+ |
| 17. F | MUD | 114 | 16 | 15 | II° (S) | None | MR‡ d 279+ |
MUD indicates matched unrelated donor; mm: mismatched; CCR: continuous complete remission; Rel-id: HLA-identical sibling; S, skin; Rel-mm: related, mismatched donor; NE, not evaluable; G, gastrointestinal; PD: progressive disease; L, liver; MOF: multiorgan failure.
Days to absolute neutrophil count (ANC) > 1 × 109/L, platelets > 20 × 109/L.
The patient had persistent disease on day 120 and received a donor lymphocyte infusion with now decreasing monoclonal bands.
Currently still decreasing monoclonal bands (patient no. 10 only positive for immunofixation).