Table 4.

Cumulative OR rate (%) in relation to treatment duration and tumor site in B-CLL patients who responded to alemtuzumab therapy

Tumor siteProportion (%) of responding patients
Wk 6Wk 12Wk 18
Blood, n = 37 1004-150 100 100  
Bone marrow, n = 30 10 45 100  
Lymph nodes, n = 27 42 69 100 
Spleen, n = 25 29 54 100 
Tumor siteProportion (%) of responding patients
Wk 6Wk 12Wk 18
Blood, n = 37 1004-150 100 100  
Bone marrow, n = 30 10 45 100  
Lymph nodes, n = 27 42 69 100 
Spleen, n = 25 29 54 100 
F4-150

Median time to CR in blood was 21 days (range, 7-63 days).

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