Table 2.

Response (%) in 38 evaluable* B-CLL patients treated with subcutaneous alemtuzumab as first-line treatment

GroupORCRPRSDPD
All patients, N = 38 87 19 68 5  
Rai stage I or II, n = 11 100 91 0  
Rai stage III or IV, n = 27 81 22 59 11 8  
Age older than 65 y, n = 20 90 20 70 5  
Age 65 years or younger, n = 18 83 17 66 11 6  
Any lymph node greater than 5 cm in diameter, n = 7 86 86 14 0  
All lymph nodes 5 cm or less in diameter, n = 24 88 21 67 
No lymphadenopathy, n = 7 86 29 57 14 
GroupORCRPRSDPD
All patients, N = 38 87 19 68 5  
Rai stage I or II, n = 11 100 91 0  
Rai stage III or IV, n = 27 81 22 59 11 8  
Age older than 65 y, n = 20 90 20 70 5  
Age 65 years or younger, n = 18 83 17 66 11 6  
Any lymph node greater than 5 cm in diameter, n = 7 86 86 14 0  
All lymph nodes 5 cm or less in diameter, n = 24 88 21 67 
No lymphadenopathy, n = 7 86 29 57 14 

SD indicates stable disease.

*

Three patients who received only 1 week of treatment were excluded from the efficacy analysis.

All CRs in this category were obtained in patients with lymph nodes < 2 cm in diameter.

or Create an Account

Close Modal
Close Modal