Peripheral blood and bone marrow values at 0, 2, 5, 8, and 11 mo in 19 imatinib mesylate–treated chronic-phase chronic myelogenous leukemia patients
. | 0 mo . | 2 mo . | 5 mo . | 8 mo . | 11 mo . | 14 mo . |
---|---|---|---|---|---|---|
WBC count × 109/L, mean (range) | 31 (8.8-94.9) | 6.4 (1.3-31.5) | 5.9 (2.2-15.3) | 5.7 (2.4-11.5) | 5.4 (2.4-10.5) | 5.3 (3.2-12.6) |
Platelet count × 109/L, mean (range) | 438 (118-1090) | 285 (48-1080) | 217 (69-359) | 206 (66-494) | 196 (58-341) | 167 (37-329) |
PB basophil count × 109/L, mean (range) | 1.008 (0-2.779) | .296 (0-4.410) | .032 (0-.237) | .015 (0-.084) | .024 (0-.105) | .018 (0-.064) |
Hemoglobin, g/L [g/dL], mean (range) | 130 [13.0] (97-166) [9.7-16.6] | 123 [12.3] (89-156) [8.9-15.6] | 126 [12.6] (94-149) [9.4-14.9] | 125 [12.5] (87-158) [8.7-15.8] | 124 [12.4] (96-149) [9.6-14.9] | 121 [12.1] (90-151) [9.0-15.1] |
Marrow cellularity, % (range) | 87 (50-100) | 52 (15-95) | 41 (5-95) | 36 (5-65) | 39 (10-60) | 40 (10-80) |
Marrow myeloid-to-erythroid ratio (range) | 11.6 (3.3-48) | 2.5 (.8-10) | 2.7 (.4-8.7) | 1.8 (.8-3.5) | 2.2 (1.0-4.1) | 1.7 (.7-3.8) |
Marrow blasts, % (range) | 3.5 (0-12) | 1.6 (0-5) | 1.6 (0-4) | 1.3 (0-5) | 0.6 (0-2) | 1.1 (0-3) |
. | 0 mo . | 2 mo . | 5 mo . | 8 mo . | 11 mo . | 14 mo . |
---|---|---|---|---|---|---|
WBC count × 109/L, mean (range) | 31 (8.8-94.9) | 6.4 (1.3-31.5) | 5.9 (2.2-15.3) | 5.7 (2.4-11.5) | 5.4 (2.4-10.5) | 5.3 (3.2-12.6) |
Platelet count × 109/L, mean (range) | 438 (118-1090) | 285 (48-1080) | 217 (69-359) | 206 (66-494) | 196 (58-341) | 167 (37-329) |
PB basophil count × 109/L, mean (range) | 1.008 (0-2.779) | .296 (0-4.410) | .032 (0-.237) | .015 (0-.084) | .024 (0-.105) | .018 (0-.064) |
Hemoglobin, g/L [g/dL], mean (range) | 130 [13.0] (97-166) [9.7-16.6] | 123 [12.3] (89-156) [8.9-15.6] | 126 [12.6] (94-149) [9.4-14.9] | 125 [12.5] (87-158) [8.7-15.8] | 124 [12.4] (96-149) [9.6-14.9] | 121 [12.1] (90-151) [9.0-15.1] |
Marrow cellularity, % (range) | 87 (50-100) | 52 (15-95) | 41 (5-95) | 36 (5-65) | 39 (10-60) | 40 (10-80) |
Marrow myeloid-to-erythroid ratio (range) | 11.6 (3.3-48) | 2.5 (.8-10) | 2.7 (.4-8.7) | 1.8 (.8-3.5) | 2.2 (1.0-4.1) | 1.7 (.7-3.8) |
Marrow blasts, % (range) | 3.5 (0-12) | 1.6 (0-5) | 1.6 (0-4) | 1.3 (0-5) | 0.6 (0-2) | 1.1 (0-3) |
WBC indicates white blood cell; PB, peripheral blood.