Table 4.

Treatment burden according to treatment phase

Protocol IaProtocol IbConsolidation blocksProtocol II, 1stProtocol II, 2nd
No. patients analyzed 182 157 124 109 31  
Red blood cells      
 Patients receiving at least 1 U, % 85 96 90 69 65  
 No. units, mean 2.9 3.1 3.7 2.4 2.1 
Platelets      
 Patients receiving at least 1 U, % 51 36 70 16 23  
 No. units, mean 4.3 3.6 5.1 3.6 3.4  
IV antibiotic therapy      
 Patients, % 46 37 82 46 74  
 Duration in days, mean 11 14 14  
Central venous line      
 Patients, % 67 75 83 80 74  
 No. days, mean 35 50 68 74 78 
Hospitalization      
 Patients, % 97 85 99 85 87  
 No. days, mean 22 14 32 11 19  
Phase duration, days      
 Scheduled by protocol 42 42 63 64 64  
 Observed, mean 46 59 73 81 89 
Protocol IaProtocol IbConsolidation blocksProtocol II, 1stProtocol II, 2nd
No. patients analyzed 182 157 124 109 31  
Red blood cells      
 Patients receiving at least 1 U, % 85 96 90 69 65  
 No. units, mean 2.9 3.1 3.7 2.4 2.1 
Platelets      
 Patients receiving at least 1 U, % 51 36 70 16 23  
 No. units, mean 4.3 3.6 5.1 3.6 3.4  
IV antibiotic therapy      
 Patients, % 46 37 82 46 74  
 Duration in days, mean 11 14 14  
Central venous line      
 Patients, % 67 75 83 80 74  
 No. days, mean 35 50 68 74 78 
Hospitalization      
 Patients, % 97 85 99 85 87  
 No. days, mean 22 14 32 11 19  
Phase duration, days      
 Scheduled by protocol 42 42 63 64 64  
 Observed, mean 46 59 73 81 89 

Mean values were estimated including only patients who actually required the specific support.

Consolidation blocks data presented pertain to the entire phase (3 blocks).

Central venous line data are cumulative.

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