Analysis of individual subclones derived from paternal peripheral blood cell DNA and in vitro colonies for the presence of the 1929T>C mutation and 4890C>A polymorphism
| . | 1929T>C mutation . | 4890C>A polymorphism . | ||
|---|---|---|---|---|
| C1929 clones (colonies)/total analyzed . | A4890 clones/total clones analyzed . | |||
| No. . | % . | No. . | % . | |
| Peripheral blood cells | ||||
| CD3+ | 13 of 54 | 24* | 27 of 53 | 48 |
| Neutrophils | 6 of 84 | 7* | 16 of 36 | 44 |
| In vitro colonies | ||||
| BFU-E | 33 of 58 | 57 | — | — |
| CFU-GM | 14 of 34 | 41 | — | — |
| . | 1929T>C mutation . | 4890C>A polymorphism . | ||
|---|---|---|---|---|
| C1929 clones (colonies)/total analyzed . | A4890 clones/total clones analyzed . | |||
| No. . | % . | No. . | % . | |
| Peripheral blood cells | ||||
| CD3+ | 13 of 54 | 24* | 27 of 53 | 48 |
| Neutrophils | 6 of 84 | 7* | 16 of 36 | 44 |
| In vitro colonies | ||||
| BFU-E | 33 of 58 | 57 | — | — |
| CFU-GM | 14 of 34 | 41 | — | — |
Difference in the percentage of mutant clones derived from CD3+ and neutrophil DNA is statistically significant (P < .001).